MIR127, microRNA 127, 406914

N. diseases: 105; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 AlteredExpression disease BEFREE miR-127 is downregulated in breast cancer, where it has been shown to suppress the proliferation, migration and invasion of breast cancer cells. 31694904 2020
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 AlteredExpression disease BEFREE miR-127 is downregulated in breast cancer, where it has been shown to suppress the proliferation, migration and invasion of breast cancer cells. 31694904 2020
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 PosttranslationalModification disease BEFREE Additionally, we also found a strong association between hypermethylation of MIR-127 and MIR-125b-1 and BC progression, particularly metastasis. 27998789 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 AlteredExpression disease BEFREE The RQ of plasma miR-127-3p in BC patients was significantly higher than that in benign breast tumor patients and healthy individuals (both P< 0.001), and there was no significant difference between benign breast tumor patients and healthy individuals (P> 0.05). 27983524 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 AlteredExpression disease BEFREE The RQ of plasma miR-127-3p in BC patients was significantly higher than that in benign breast tumor patients and healthy individuals (both P< 0.001), and there was no significant difference between benign breast tumor patients and healthy individuals (P> 0.05). 27983524 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 PosttranslationalModification disease BEFREE Additionally, we also found a strong association between hypermethylation of MIR-127 and MIR-125b-1 and BC progression, particularly metastasis. 27998789 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 Biomarker disease BEFREE Therefore, miR-127 may be a potential biomarker for predicting the survival of BC patients and might be a molecular target for treatment of human BCs. 25477702 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 Biomarker disease BEFREE Therefore, miR-127 may be a potential biomarker for predicting the survival of BC patients and might be a molecular target for treatment of human BCs. 25477702 2014
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 AlteredExpression disease BEFREE Over-expression of miR-127 or depletion of BCL6 inhibits breast cancer cell proliferation. 24282530 2013
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 Biomarker disease BEFREE Circulating miR-127-3p, miR-376a and miR-652, selected as candidates from a miRNA array-based screening, were found to be associated with breast cancer for the first time (n = 417). 24194846 2013
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 AlteredExpression disease BEFREE Moreover, overexpression of miR-127 reduced the in vitro migration and proliferation ability of breast cancer cell MDA-MB-231. 24155205 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 AlteredExpression disease BEFREE Moreover, overexpression of miR-127 reduced the in vitro migration and proliferation ability of breast cancer cell MDA-MB-231. 24155205 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 AlteredExpression disease BEFREE Over-expression of miR-127 or depletion of BCL6 inhibits breast cancer cell proliferation. 24282530 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 Biomarker disease BEFREE Circulating miR-127-3p, miR-376a and miR-652, selected as candidates from a miRNA array-based screening, were found to be associated with breast cancer for the first time (n = 417). 24194846 2013
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.370 Biomarker disease CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.370 Biomarker disease CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276 2010
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 AlteredExpression disease BEFREE Importantly, a regulatory loop involving the inflammatory signals NF-κB, miR-127 and tumor necrosis factor alpha-induced protein 3 was uncovered as a self-reinforcing circuitry that ensured an aggressive transition in lung cancer. 27869168 2017
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker disease CTD_human Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA. 25105010 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.300 Biomarker disease CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017
CUI: C3501843
Disease: Nonmedullary Thyroid Carcinoma
Nonmedullary Thyroid Carcinoma
0.300 Biomarker disease CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017
Familial Nonmedullary Thyroid Cancer
0.300 Biomarker disease CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017
CUI: C0007095
Disease: Carcinoid Tumor
Carcinoid Tumor
0.300 Biomarker phenotype CTD_human Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA. 25105010 2014
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 Biomarker group CTD_human Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA. 25105010 2014
Respiratory Distress Syndrome, Adult
0.300 Biomarker disease CTD_human MicroRNA and mRNA expression profiling in rat acute respiratory distress syndrome. 25070658 2014