MIR206, microRNA 206, 406989

N. diseases: 226; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 AlteredExpression disease BEFREE Functional studies demonstrated that miR-206 overexpression significantly suppresses GC cell proliferation, migration, and invasion, and induces apoptosis in vitro. 30774372 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 Biomarker disease BEFREE Thus, we concluded that miR‑206 inhibits formation of CICs by targeting EHF in gastric cancer. 28714026 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 Biomarker disease BEFREE ROC curve analysis showed that serum miRNA-206 was a useful marker for GC diagnosis, and could discriminate between recurred and non-recurred patients. 27614739 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 Biomarker disease BEFREE LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer. 27192121 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 Biomarker disease BEFREE MiR-206 inhibited GC metastasis by negatively regulating expression of PAX3. 25653235 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 Biomarker disease BEFREE Our data provide evidence that the dysregulation of miR-206-CCND2 axis may contribute to the aggressive progression and poor prognosis of human gastric cancer in clinical settings. 25960238 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 AlteredExpression disease BEFREE Our results demonstrated that miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors. 26186594 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 AlteredExpression disease BEFREE Furthermore, multivariate analysis showed that miR-206 expression was an independent prognostic factor for patients with gastric cancer. 23751352 2013
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.090 Biomarker disease BEFREE miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2. 23348698 2013