MIR21, microRNA 21, 406991

N. diseases: 726; N. variants: 2
Disease: Kidney Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.320 Biomarker group BEFREE Previously, it was reported that kidney microRNA-21 (miR-21) expression is significantly increased in <i>Col4α3</i><sup>-/-</sup> mice, and administration of anti-miR-21 oligonucleotides (anti-miR-21) attenuates kidney disease progression in <i>Col4α3</i><sup>-/-</sup> mice, indicating that miR-21 is a viable therapeutic target for Alport syndrome. 30808234 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.320 Biomarker group BEFREE Recent studies have indicated that microRNA-21 (miR-21) is involved in the inflammatory response in relation to renal disease. 28214900 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.320 Biomarker group CTD_human Increased circulating miR-21 levels are associated with kidney fibrosis. 23469132 2013