MIR222, microRNA 222, 407007

N. diseases: 210; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.340 AlteredExpression disease BEFREE MiR-30b, miR-30c, miR-221 and miR-222 are known to induce gefitinib resistance in lung cancer cell lines with activation of mutations in the epidermal growth factor receptor (EGFR). 31447008 2019
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.340 AlteredExpression disease BEFREE Immunohistochemistry showed that the expression of miR-222 in lung cancer tissue was significantly higher, but TIMP3 was lower than that in normal lung tissue (<i>P</i> = 0.0001 for the former and <i>P</i> = 0.0002 for the latter). 30233216 2018
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.340 Biomarker disease BEFREE In conclusion, our data are the first to show tumor-suppressive effects of miR-221 and miR-222 on lung cancer, warranting testing their potential as therapeutics for the disease. 25641933 2015
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.340 Biomarker disease CTD_human Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA. 25105010 2014
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.340 AlteredExpression disease BEFREE High-mobility group A1 proteins enhance the expression of the oncogenic miR-222 in lung cancer cells. 21656127 2011