SMAD2, SMAD family member 2, 4087

N. diseases: 289; N. variants: 8
Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.220 Biomarker group BEFREE TGF-β inhibition via overexpression of SMAD7 (or knockdown of SMAD2, SMAD3, or SMAD4) consistently reduced formation and growth of liver tumors in mice that expressed activated RAS plus shRNA against p53, or in mice that expressed activated RAS and TAZ. 28734833 2017
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.220 AlteredExpression group BEFREE Curcumin downregulates the expression of Snail via suppressing Smad2 pathway to inhibit TGF-β1-induced epithelial-mesenchymal transitions in hepatoma cells. 29312546 2017
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.220 Biomarker group RGD [Changes in TGF-beta1/Smads signaling pathway in rats with chemical hepatocarcinogenesis]. 18971187 2008