Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease CLINGEN SMAD2 Mutations Are Associated with Arterial Aneurysms and Dissections. 26247899 2015
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease CLINGEN Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. 19224541 2009
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease CLINGEN SMAD proteins control DROSHA-mediated microRNA maturation. 18548003 2008
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease CLINGEN Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. 11779503 2001
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease CLINGEN TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. 9311995 1997
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease CLINGEN MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling. 8980228 1996
Familial thoracic aortic aneurysm and aortic dissection
0.500 Biomarker disease GENOMICS_ENGLAND