SMAD4, SMAD family member 4, 4089

N. diseases: 575; N. variants: 144
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.200 Biomarker disease BEFREE Using cell viability assays, the effect of these compounds was validated on four colon cancer cell lines: HCT-116 and HCT-15 (SMAD4-expressing), and HT-29 and COLO-205 (SMAD4-negative). 20331650 2010
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.200 Biomarker disease BEFREE We investigated endogenous Smad4 expression in 7 human colorectal cancer cell lines, and found that six of colon cancer cell lines existed with loss of Smad4. 25680269 2015