SMAD6, SMAD family member 6, 4091

N. diseases: 93; N. variants: 26
Disease: Nephritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027697
Disease: Nephritis
Nephritis 		0.200 Biomarker disease RGD In order to investigate whether Smad6 and 7 are also involved in the negative feedback loop of TGF-beta signaling in vivo, we examined the changes of mRNA levels of these Smads in the glomeruli of rat anti-Thy1 (1-22-3) nephritis, a model where the expression of TGF-beta in the glomeruli has been shown to be most up-regulated from day 4 to 14 after the antibody injection. 11170839 2000