SMAD7, SMAD family member 7, 4092

N. diseases: 269; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. 30529582 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Novel Common Genetic Susceptibility Loci for Colorectal Cancer. 29917119 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. 30104761 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. 29471430 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. 26965516 2016
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease BEFREE Both the SMAD7 rs4939827 TT genotype and the CHI3L1 rs4950928 C allele were associated with the rectal but not the colon cancer. 26779637 2016
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Genome-wide association study of colorectal cancer in Hispanics. 27207650 2016
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. 25990418 2015
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Genome-wide association study of colorectal cancer identifies six new susceptibility loci. 26151821 2015
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians. 24448986 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. 24836286 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 Biomarker disease BEFREE A functional role for Smad7 in sustaining colon cancer cell growth and survival. 24556688 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. 23266556 2013
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease BEFREE SMAD7 SNPs were associated with colorectal cancer risk in the Colon Cancer Family Registry. 23560096 2013
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 Biomarker disease BEFREE These results suggest that miR-25 may function as a tumor suppressor by targeting Smad7 in colon cancer. 23435373 2013
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Meta-analysis of new genome-wide association studies of colorectal cancer risk. 21761138 2012
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 Biomarker disease BEFREE These results corroborate the findings of GWAS in colon cancer pointing to SMAD7 and reinforce interest in SNPs in this gene. 20124488 2010
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease BEFREE Association of common genetic variants in SMAD7 and risk of colon cancer. 19357349 2009
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. 18372901 2008
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation disease GWASCAT A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. 17934461 2007
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 Biomarker disease HPO