|
Malaria, Cerebral
|
0.010 |
Biomarker
|
disease |
BEFREE |
Elevated cerebrospinal fluid tau protein concentrations on admission are associated with long-term neurologic and cognitive impairment in Ugandan children with cerebral malaria.
|
31044219 |
2020 |
|
Multiple Sclerosis, Relapsing-Remitting
|
0.010 |
Biomarker
|
disease |
BEFREE |
Serum and saliva total tau protein as a marker for relapsing-remitting multiple sclerosis.
|
31733529 |
2020 |
|
Behavior Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Alzheimer's Disease (AD) is an age-dependent neurodegenerative disorder, the most common type of dementia that is clinically characterized by the presence of beta-amyloid (Aβ) extracellularly and intraneuronal tau protein tangles that eventually leads to the onset of memory and cognition impairment, development of psychiatric symptoms and behavioral disorders that affect basic daily activities.
|
31642777 |
2019 |
|
Encephalitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Tau protein concentration in CSF before treatment did not differ significantly between the examined groups, while its concentration was significantly higher in encephalitis group than in CG after 14 days of treatment.
|
30721423 |
2019 |
|
Tick-Borne Encephalitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The concentration of tau protein in CSF was determined using Fujirebio tests (Ghent, Belgium) in 35 patients with TBE: group I-patients with meningitis (n = 16); group II-patients with meningoencephalitis (n = 19).
|
30721423 |
2019 |
|
Epilepsy, Temporal Lobe
|
0.010 |
Biomarker
|
disease |
BEFREE |
Association of cerebrospinal fluid zinc-α2-glycoprotein and tau protein with temporal lobe epilepsy and related white matter impairment.
|
30964766 |
2019 |
|
melanoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Results revealed that high expression of the MAPT gene is very strongly associated with increased overall and disease‑free survival in LGG but not in breast cancer or melanoma.
|
30535461 |
2019 |
|
Meningitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The concentration of tau protein in CSF was determined using Fujirebio tests (Ghent, Belgium) in 35 patients with TBE: group I-patients with meningitis (n = 16); group II-patients with meningoencephalitis (n = 19).
|
30721423 |
2019 |
|
Meningoencephalitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The concentration of tau protein in CSF was determined using Fujirebio tests (Ghent, Belgium) in 35 patients with TBE: group I-patients with meningitis (n = 16); group II-patients with meningoencephalitis (n = 19).
|
30721423 |
2019 |
|
Vascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Diagnosis of AD can be made biologically with detection of amyloid and tau proteins in the cerebrospinal fluid (CSF) and vascular disease can be identified with diffusion tensor imaging (DTI).
|
31374883 |
2019 |
|
Pleocytosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Correlation analysis showed that in TBE patients (both meningoencephalitis and meningitis groups), CSF pleocytosis before treatment correlated negatively with tau protein concentration in CSF.
|
30721423 |
2019 |
|
Malignant neoplasm of brain
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, the role of microtubule‑associated protein Tau (MAPT) expression in brain cancer is largely unknown.
|
30535461 |
2019 |
|
Metastatic malignant neoplasm to brain
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The prognostic value of the Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases.
|
30700265 |
2019 |
|
Psychiatric symptom
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Alzheimer's Disease (AD) is an age-dependent neurodegenerative disorder, the most common type of dementia that is clinically characterized by the presence of beta-amyloid (Aβ) extracellularly and intraneuronal tau protein tangles that eventually leads to the onset of memory and cognition impairment, development of psychiatric symptoms and behavioral disorders that affect basic daily activities.
|
31642777 |
2019 |
|
Drug usage
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Red Blood Cell Omega-3 Fatty Acid Composition and Psychotropic Drug Use in Older Adults: Results from the MAPT Study.
|
31641729 |
2019 |
|
Cerebral dysfunction
|
0.010 |
Biomarker
|
disease |
BEFREE |
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β and tau proteins, which are believed to lead to neural damage that translates into brain dysfunction and cognitive deficits.
|
30599271 |
2019 |
|
Large cell carcinoma of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our findings suggested that specific manipulation of MAPT-targeting miRNAs may be a novel strategy to overcome paclitaxel resistance in patients with NSCLC especially large-cell lung carcinoma.
|
31496800 |
2019 |
|
Malignant neoplasm of prostate
|
0.010 |
Biomarker
|
disease |
BEFREE |
The results of our study identify MAPT, as a moderate prognostic marker in prostate cancer, whose clinical impact, however, may be limited due to the rarity and heterogeneity of its expression.
|
30823906 |
2019 |
|
Prostate carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The results of our study identify MAPT, as a moderate prognostic marker in prostate cancer, whose clinical impact, however, may be limited due to the rarity and heterogeneity of its expression.
|
30823906 |
2019 |
|
Ischemic stroke
|
0.010 |
Biomarker
|
disease |
BEFREE |
Secondly, we summarized the potential regulatory mechanisms of tau protein in the process of ischemic stroke.
|
31841442 |
2019 |
|
Hospital acquired pneumonia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Patients with nosocomial pneumonia exhibit elevated levels of neurotoxic amyloid and tau proteins in the cerebrospinal fluid (CSF).
|
31211919 |
2019 |
|
Healthcare associated pneumonia
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Patients with nosocomial pneumonia exhibit elevated levels of neurotoxic amyloid and tau proteins in the cerebrospinal fluid (CSF).
|
31211919 |
2019 |
|
Autism Spectrum Disorders
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Network analysis of both regions of ASD brain showed up-regulation of multiple pre- and post-synaptic membrane or scaffolding proteins including glutamatergic ion channels and related proteins, up-regulation of proteins involved in intracellular calcium signaling, and down-regulation of neurofilament proteins, with DLG4 and MAPT as major hub proteins in BA19 and CB protein interaction networks, respectively.
|
31511657 |
2019 |
|
Neurodevelopmental Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Upregulated levels and pathological aggregation of abnormally phosphorylated Tau-protein in children with neurodevelopmental disorders.
|
30550860 |
2019 |
|
Diabetic encephalopathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study was designed to investigate the effect of metformin on hyperphosphorylated tau proteins in diabetic encephalopathy (DE) by regulating autophagy clearance. db/db mice were randomly divided into four groups, db/+ mice were used as control group.
|
30219731 |
2019 |