ARSD, arylsulfatase D, 414

N. diseases: 163; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. 31621020 2020
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE As to anxiety, it is not the main characteristics of ASD, but represents one of the most common its co morbidities. 31437571 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Group differences in brain activation disappeared when either alexithymia or anxiety - both elevated in the ASD group - were controlled for. 29683406 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE Symptoms of ASD were found to influence elevated levels of parent-rated GAD indirectly through greater levels of sensory avoiding, and auditory-specific sensory behaviours correlated with parent-rated anxiety more strongly than other sensory modalities. 30771129 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE There was no significant difference in risks for ADHD (OR = 1.563; 95% CI, 1.382-1.769); sleep disorders (OR = 2.100; 95% CI, 1.322-3.336); anxiety (OR = 1.339; 95% CI, 1.062-1.687); depression (OR = 1.402 95% CI, 1.256-1.565); conduct disorder (OR = 1.494 95% CI, 1.230-1.815); or ASD (OR = 2.574; 95% CI, 1.469-4.510; <i>Q</i><sub>b</sub> = 8.344, <i>p</i> = 0.138). 31447731 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Our findings emphasise the need to provide timely assessment and treatment of anxiety and depression in ASD. 31190198 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Maternal anxiety or depression was associated with 2.7 times the odds (95% confidence interval: 1.4, 5.3) of Type 4 or Dysregulated ASD in the child; maternal anxiety and depression was associated with 4.4 times the odds (95% confidence interval: 1.4, 14.0) of Type 4 or Dysregulated ASD in the child. 30128718 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE As expected, many of these include animal model equivalents of the "core" phenotypes associated with ASD, such as impairments in social behavior and repetitive behavior, as well as several comorbid features of ASD including anxiety, seizures, and motor-control deficits. 30911366 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE We conducted a meta-synthesis to explore what strategies parents use to manage irritability, non-compliance, challenging behaviour and anxiety in their children with ASD. 29222612 2018
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE Youth with ASD without co-occurring intellectual disability experience high levels of intolerance of uncertainty (IU), which is related to anxiety. 29316350 2018
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE These findings bear strong resemblance to the pattern seen in ASD and emphasize the need for development of anxiety interventions that attempt to reduce negative beliefs about unpredictable situations in WS. 29948532 2018
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Encouragingly, our findings suggest that HADS provides a reliable and valid assessment of anxiety and depression in ASD. 28922575 2018
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Brief Report: Bullying and Anxiety in High-Functioning Adolescents with ASD. 29152669 2018
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Results suggest that youth with ASD and co-occurring anxiety have a distinct neurodevelopmental trajectory. 28689329 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE In this cross-sectional study, we assessed social media use, anxiety and friendship quality in 44 adolescents with ASD, and 56 clinical comparison controls. 28616856 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Findings demonstrated that young people with ASD can self-report and show insight in to their RRB, and replicated previous findings based on parent report showing a significant positive relationship between RRB and anxiety. 28238024 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Key themes include recognition of the importance individual differences in aetiology and presentation of anxiety in ASD, the need for a more nuanced understanding of the interactions between anxiety and characteristics of ASD and the need to develop appropriately adapted treatments. 28988366 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE This study evaluated change in social skills during a randomized controlled trial of CBT and during the 1-year follow-up for 25 adolescents with ASD and anxiety. 27040557 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Thirty-five young people (11-14 years; IQ > 70) with ASD and elevated teacher or parent reported anxiety were randomly assigned to 6 sessions of the Exploring Feelings CBT intervention (Attwood in Exploring feelings (anxiety). 27440250 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE This follow-up study investigated changes in caregiver-reported anxiety in 54 non-referred youth with ASD after 10-19 months. 28451947 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE The study's limitations, the use of the SCAS-P to screen for DSM-derived anxiety problems in ASD and future research directions are discussed.Autism Res 2017, 10: 1629-1652. 28574646 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE The aim of the present study was to examine the association between a variable number tandem repeat (VNTR) functional polymorphism in the promoter region of the MAO-A gene and severity of ADHD and anxiety in boys with ASD. 18566880 2009