|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Parenting Strategies Used by Parents of Children with ASD: Differential Links with Child Problem Behaviour.
|
31676915 |
2020 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Children with ASD often display behavior problems that can lead to academic and social disruptions.
|
31676916 |
2020 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
We studied the possible preventive effect of the methyl donor for epigenetic enzymatic reactions, S-adenosine methionine (SAM), on ASD like behavioral changes and on redox potential in the brain and liver in this model.
|
29343446 |
2020 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
One moderating effect was identified, with child presence during conflict related to higher behavior problems according to mothers in the ASD group but not those in the comparison group.
|
30407023 |
2019 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
We investigated the mechanism of impact of poor communication skills and emotional and behavioural problems in children with ASD (22-61 months) on parental psychological distress.
|
31368058 |
2019 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Teaching Robotics Coding to a Student with ASD and Severe Problem Behavior.
|
30734176 |
2019 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
The current study examined bidirectional effects between parenting stress and three domains of child functioning (ASD symptoms, internalizing behavior problems, and externalizing behavior problems) across four time points in 188 families of children with ASD (ages 5-12 years).
|
30623270 |
2019 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
In this study we used: i) summary statistics from the Psychiatric Genomics Consortium (PGC) GWAS for seven psychiatric disorders; ii) examined all reported CNTNAP2 structural variants in patients and controls; iii) performed cross-disorder analysis of functional or previously associated SNPs; and iv) conducted burden tests for pathogenic rare variants using sequencing data (4,483 ASD and 6,135 schizophrenia cases, and 13,042 controls).
|
30586385 |
2018 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Children with parent-reported ASD diagnosis were more likely to have greater health care needs and difficulties accessing health care than children with other emotional or behavioral disorders (attention-deficit/hyperactivity disorder, anxiety, behavioral or conduct problems, depression, developmental delay, Down syndrome, intellectual disability, learning disability, Tourette syndrome) and children without these conditions.
|
30478241 |
2018 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Interventions to develop adapting/coping mechanisms may be important for mitigation of problem behaviors across the spectrum of individuals with ASD.
|
28597186 |
2018 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
This study addresses how the behavioral changes after treatment for ASD reflect underlying brain changes.
|
29517857 |
2018 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
School-based interventions intended to decrease problem behavior for individuals with ASD were reviewed; 46 articles including 84 single case designs and 87 participants were analyzed regarding participant demographics, settings and implementers, intervention components, and study characteristics.
|
29704142 |
2018 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Results suggest complex parenting demands in children with ASD and problem behaviour.
|
29222612 |
2018 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Findings highlight feasibility of using a broadband social-emotional competence and behavior problem screener to improve early detection of ASD.
|
28181053 |
2017 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Additionally, deep phenotyping revealed overlapping behavioral problems (ASD, ADHD, and anxiety disorders), hypotonia, broad-based gait, facial dysmorphisms, and periods of fever and vomiting.
|
28343630 |
2017 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
We conclude that "modeling a model", in this case 22q11DS as a model for idiopathic ASD, ADHD and SCZ, as well as other behavioral disorders like anxiety frequently seen in 22q11DS patients, in genetically engineered mice provides a foundation for understanding the causes and improving diagnosis and therapy for these disorders of cortical circuit development.
|
25866365 |
2015 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Brief report: impact of child problem behaviors and parental broad autism phenotype traits on substance use among parents of children with ASD.
|
24805795 |
2014 |
|
Abnormal behavior
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
This review addresses the particular issues that attend gene discovery in neuropsychiatric and neurodevelopmental disorders and ASDs in particular, summarizes recent findings in human genetics broadly that are driving the reevaluation of the conventional wisdom regarding the allelic architecture of common psychiatric conditions, reviews selected discoveries in ASDs and their relevance to models of pathology, highlights the conceptual and practical issues raised by the observation of a convergence of ASD genetic risks with distinct psychiatric disorders, and considers the important interplay of studies of neurobiology and genetics in clarifying and extending our understanding of social disability syndromes.
|
22037497 |
2011 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Our results support a growing body of research indicating that concomitant behavioral disturbances in children with ASD warrant consideration as clinical phenotypes, but replication with independent samples is necessary to confirm this preliminary finding.
|
18566880 |
2009 |