ARSD, arylsulfatase D, 414

N. diseases: 163; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE The aim of this study is to investigate the association between prematurity and diagnosis of neurodevelopmental disorders (ND) (attention deficit/hyperactivity disorder [ADHD] or autism spectrum disorder [ASD]) in Brazilian children and adolescents. 31552529 2020
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE Familial disorders with onset in childhood (e.g., autism spectrum disorder [ASD]) are promising targets for presymptomatic prediction; however, little is known about parent perceptions of risk to their children in the presymptomatic period. 31764985 2020
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE In the present study, language performance on standardized assessments (e.g., overall verbal performance, receptive and expressive vocabulary) and spontaneous language produced in play was compared between preschool-aged boys with autism spectrum disorder (<sub>n</sub>ASD, n = 25) and boys with fragile X syndrome (FXS, n = 16). 30783899 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE We included 2- to 5-year-old children whose parent completed all items on the Children's Sleep Habits Questionnaire (CSHQ) in a multisite case-control study: 522 children with ASD; 228 children with other developmental delays and disorders with autism spectrum disorder characteristics (DD w/ASD); 534 children with other developmental delays and disorders without autism spectrum disorder characteristics (DD w/o ASD); and 703 POP. 30745433 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Infants with an older sibling with an Autism Spectrum Disorder diagnosis (Sibs ASD) are at high risk for language delay (LD) as well as infants born preterm, especially those with an extremely low gestational age (ELGA, GA ≤ 28 weeks). 31649572 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Here, we aimed to investigate differences in functional brain network integrity between traditional diagnostic categories (autism spectrum disorder [ASD], attention-deficit/hyperactivity disorder [ADHD], typically developing [TD]) and carefully consider the impact of comorbid ASD and ADHD on functional brain network integrity in a sample adequately powered to detect large effects. 30708240 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Participants included 100 preschoolers (M<sub>age</sub> = 4.73, 75% Male, 79% Hispanic) including 37 with autism spectrum disorder and attention-deficit/hyperactivity disorder (ASD+ADHD), 32 with ADHD-only, and 31 typically developing children. 30973019 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Parents of 5- to 12-year-old children (half had been diagnosed with autism spectrum disorder [ASD] and half were typically developing) provided reports of the most significant marital conflict of the day and ratings of child behaviors problems on a daily basis for 14 days. 30407023 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Autism Spectrum Disorder Decision Tree Subgroups Predict Adaptive Behavior and Autism Severity Trajectories in Children with ASD. 30511124 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 AlteredExpression group BEFREE Therefore, the purpose of this study was to meta-analytically aggregate study effect sizes to more accurately calculate the degree to which ASD-Sibs function similarly or differently compared to siblings of people who do not have ASD. 30178117 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE The results suggest that caution be exercised in generalizing findings from ASD-sib samples to other samples of children with ASD. 30663862 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE A total of 144 toddlers (40 typically developing, 58 with autism spectrum disorder [ASD], 46 with developmental delay [DD]) participated at 24 and 31 months. 28991358 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE A parent or legal guardian reported neurodevelopmental concerns in 4 domains (speech, learning and attentional difficulties, and autism spectrum disorder [ASD]) and completed the Personal Adjustment and Role Skills Scale to assess psychosocial adjustment. 31594858 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE In this UK population-based cohort study, 7921 mothers with genotype data from the Avon Longitudinal Study of Parents and Children (ALSPAC) underwent testing for association of maternal PRS for attention-deficit/hyperactivity disorder (ADHD PRS), autism spectrum disorder (ASD PRS), and schizophrenia (SCZ PRS) with 32 early-life exposures. 31042271 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE To examine Facial Emotion Recognition (FER) and visual scanning behavior (eye-tracking) during FER in women long-term recovered from teenage-onset anorexia nervosa (recAN) with and without autism spectrum disorderASD) and age-matched comparison women (COMP), using a sensitive design with facial emotion expressions at varying intensities in order to approximate real social contexts. 30828832 2019
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Brief Report: Memory for Self-Performed Actions in Adults with Autism Spectrum Disorder: Why Does Memory of Self Decline in ASD? 29623564 2018
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE Autism spectrum disorder (ASD or autism) is a neurodevelopmental condition that affects over 1% of the population worldwide. 29496150 2018
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Purpose To identify developmental neuroradiologic findings in a large cohort of carriers who have deletion and duplication at 16p11.2 (one of the most common genetic causes of autism spectrum disorder [ASD]) and assess how these features are associated with behavioral and cognitive outcomes. 28786752 2018
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE We attempted to evaluate the ability of 125 preschool and school children with autism spectrum disorder (ASD children) to understand the intentions of those speaking to them using prosody of the voice, by comparing it with that of 119 typically developing children (TDC) and 51 development-age-matched children with attention deficit hyperactivity disorder (ADHD children), and to explore, based on the results, a method for objective evaluation of children with ASD in the early and later periods of childhood. 28774670 2017
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE <b>Highlights</b> Autism spectrum disorder (ASD) has a prevalence of 1 in 68 children in the United States.ASDs are highly heterogeneous in their genetic basis.ASDs share common features at the cellular and molecular levels in the brain.Most ASD genes are implicated in neurogenesis, structural maturation, synaptogenesis and function. 29209173 2017
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE Advances in genome-wide technology, coupled with the availability of large cohorts, are finally yielding a steady stream of autism spectrum disorder (ASD) genes carrying mutations of large effect. 25464374 2015
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 Biomarker group BEFREE Predicting social impairment and ASD diagnosis in younger siblings of children with autism spectrum disorder. 19449096 2009
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder
0.100 GeneticVariation group BEFREE This study examined whether secondary medical diagnoses that affect CNS function (i.e., seizures, malformations, or genetic disorders), are more likely to occur in individuals with fragile X syndrome (FXS) and autism spectrum disorder (FXS + ASD) or FXS alone. 18627038 2008