ARSD, arylsulfatase D, 414

N. diseases: 163; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. 31621020 2020
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 GeneticVariation group BEFREE The sample (n = 80) included 40 girls and 40 boys, ages 6-12 years, with ASD (without ID) matched on age and IQ. 31278524 2019
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. 30701432 2019
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 GeneticVariation group BEFREE This study examined informant discrepancies for parent and teacher adaptive behavior ratings of 103 children, ages 6-12 years, with ASD (without intellectual disability). 30673911 2019
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE Cognitive Mediators of School-Related Socio-Adaptive Behaviors in ASD and Intellectual Disability Pre- and Adolescents: A Pilot-Study in French Special Education Classrooms. 31766578 2019
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE We found that pathogenic point mutations affecting AP1S2 are associated with dysmorphic features and neurodevelopmental problems, which included highly variable mental retardation (MR), delayed in walking, abnormal speech, hypotonia, abnormal brain, abnormal behavior including aggressive behavior, ASD, self-abusive, and abnormal gait. 30714330 2019
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE Findings suggest a wide range of co-occurring psychopathology and high degree of maladaptive behavior among minimally verbal children and adolescents with ASD, which are not directly attributable to autism symptom severity, intellectual disability or limitations in adaptive functioning. 30833910 2019
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 AlteredExpression group BEFREE Youth with ASD without co-occurring intellectual disability experience high levels of intolerance of uncertainty (IU), which is related to anxiety. 29316350 2018
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE The current pilot study examined the feasibility of conducting an RCT to investigate the effectiveness of RIT for improving social functioning and challenging behaviors in 20 adolescents with ASD and severe ID in a residential program.The assessment protocol was feasible. 27715368 2017
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE Childhood celiac disease was identified as a risk factor for mood disorders, anxiety disorders, eating disorders, behavioral disorders, ADHD, ASD, and intellectual disability. 28283256 2017
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE Nonparametric analyses suggest distinct trajectories and early cognitive abilities for deletion carriers who are ultimately diagnosed with intellectual disability and developmental coordination disorder as well as distinct trajectories and early social communication and cognitive abilities for duplication carriers diagnosed with ASD and intellectual disability. 28349640 2017
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.100 Biomarker group BEFREE Together, these results support a model where the DIA1 and DIA1R gene products regulate molecular traffic through the cellular secretory pathway or affect the function of secreted factors, and functional deficits cause disorders with ASD-like symptoms and/or mental retardation. 21264219 2011