|
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched.
|
31621020 |
2020 |
|
Anxiety Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Anxiety disorders were more common in full siblings and half-siblings of people with ASD.The implications of this are explored.
|
31621020 |
2020 |
|
Atrial Septal Defects
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We aimed to develop and internally validate a scoring system, the adult spinal deformity surgical decision-making (ASD-SDM) score, to guide the decision-making process for ASD patients aged above 40 years.
|
31317308 |
2020 |
|
Schizophrenia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The lack of any association, when considered with positive findings seen in ASD and schizophrenia, and negative findings in bipolar disorder suggests different pathways linking maternal immune activation and development of various neuropsychiatric disorders.
|
31312974 |
2020 |
|
Schizophrenia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Using a functional genomics approach, we integrated transcriptomic data from the developing human brain, genome-wide association findings for SCZ and ASD, protein interaction data, and gene expression signatures from SCZ and ASD postmortem cortex to 1) organize genes into the developmental cellular and molecular systems within which they operate, 2) identify neurodevelopmental processes associated with polygenic risk for SCZ and ASD across the allelic frequency spectrum, and 3) elucidate pathways and individual genes through which 22q11.2 copy number variants may confer risk for each disorder.
|
31500805 |
2020 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Parenting Strategies Used by Parents of Children with ASD: Differential Links with Child Problem Behaviour.
|
31676915 |
2020 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Children with ASD often display behavior problems that can lead to academic and social disruptions.
|
31676916 |
2020 |
|
Abnormal behavior
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
We studied the possible preventive effect of the methyl donor for epigenetic enzymatic reactions, S-adenosine methionine (SAM), on ASD like behavioral changes and on redox potential in the brain and liver in this model.
|
29343446 |
2020 |
|
Pervasive Development Disorder
|
0.100 |
Biomarker
|
group |
BEFREE |
The aim of this study is to investigate the association between prematurity and diagnosis of neurodevelopmental disorders (ND) (attention deficit/hyperactivity disorder [ADHD] or autism spectrum disorder [ASD]) in Brazilian children and adolescents.
|
31552529 |
2020 |
|
Pervasive Development Disorder
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Familial disorders with onset in childhood (e.g., autism spectrum disorder [ASD]) are promising targets for presymptomatic prediction; however, little is known about parent perceptions of risk to their children in the presymptomatic period.
|
31764985 |
2020 |
|
Attention deficit hyperactivity disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study is to investigate the association between prematurity and diagnosis of neurodevelopmental disorders (ND) (attention deficit/hyperactivity disorder [ADHD] or autism spectrum disorder [ASD]) in Brazilian children and adolescents.
|
31552529 |
2020 |
|
Autism Spectrum Disorders
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Familial disorders with onset in childhood (e.g., autism spectrum disorder [ASD]) are promising targets for presymptomatic prediction; however, little is known about parent perceptions of risk to their children in the presymptomatic period.
|
31764985 |
2020 |
|
Autism Spectrum Disorders
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We aimed to develop and internally validate a scoring system, the adult spinal deformity surgical decision-making (ASD-SDM) score, to guide the decision-making process for ASD patients aged above 40 years.
|
31317308 |
2020 |
|
Autism Spectrum Disorders
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study is to investigate the association between prematurity and diagnosis of neurodevelopmental disorders (ND) (attention deficit/hyperactivity disorder [ADHD] or autism spectrum disorder [ASD]) in Brazilian children and adolescents.
|
31552529 |
2020 |
|
Autism Spectrum Disorders
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The findings of this study suggest that the aforementioned five reported ASD genes and JAK2 and MAPK7 may be related to ASD susceptibility.
|
31838722 |
2020 |
|
Autism Spectrum Disorders
|
0.100 |
Biomarker
|
disease |
BEFREE |
Using a functional genomics approach, we integrated transcriptomic data from the developing human brain, genome-wide association findings for SCZ and ASD, protein interaction data, and gene expression signatures from SCZ and ASD postmortem cortex to 1) organize genes into the developmental cellular and molecular systems within which they operate, 2) identify neurodevelopmental processes associated with polygenic risk for SCZ and ASD across the allelic frequency spectrum, and 3) elucidate pathways and individual genes through which 22q11.2 copy number variants may confer risk for each disorder.
|
31500805 |
2020 |
|
ATRIAL SEPTAL DEFECT 1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We aimed to develop and internally validate a scoring system, the adult spinal deformity surgical decision-making (ASD-SDM) score, to guide the decision-making process for ASD patients aged above 40 years.
|
31317308 |
2020 |
|
Intellectual Disability
|
0.100 |
Biomarker
|
group |
BEFREE |
Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability.
|
31621020 |
2020 |
|
Anxiety
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
As to anxiety, it is not the main characteristics of ASD, but represents one of the most common its co morbidities.
|
31437571 |
2019 |
|
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Group differences in brain activation disappeared when either alexithymia or anxiety - both elevated in the ASD group - were controlled for.
|
29683406 |
2019 |
|
Anxiety
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Symptoms of ASD were found to influence elevated levels of parent-rated GAD indirectly through greater levels of sensory avoiding, and auditory-specific sensory behaviours correlated with parent-rated anxiety more strongly than other sensory modalities.
|
30771129 |
2019 |
|
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
There was no significant difference in risks for ADHD (OR = 1.563; 95% CI, 1.382-1.769); sleep disorders (OR = 2.100; 95% CI, 1.322-3.336); anxiety (OR = 1.339; 95% CI, 1.062-1.687); depression (OR = 1.402 95% CI, 1.256-1.565); conduct disorder (OR = 1.494 95% CI, 1.230-1.815); or ASD (OR = 2.574; 95% CI, 1.469-4.510; <i>Q</i><sub>b</sub> = 8.344, <i>p</i> = 0.138).
|
31447731 |
2019 |
|
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our findings emphasise the need to provide timely assessment and treatment of anxiety and depression in ASD.
|
31190198 |
2019 |
|
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Maternal anxiety or depression was associated with 2.7 times the odds (95% confidence interval: 1.4, 5.3) of Type 4 or Dysregulated ASD in the child; maternal anxiety and depression was associated with 4.4 times the odds (95% confidence interval: 1.4, 14.0) of Type 4 or Dysregulated ASD in the child.
|
30128718 |
2019 |
|
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
As expected, many of these include animal model equivalents of the "core" phenotypes associated with ASD, such as impairments in social behavior and repetitive behavior, as well as several comorbid features of ASD including anxiety, seizures, and motor-control deficits.
|
30911366 |
2019 |