Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The present study aimed to identify the association between MBL2 gene polymorphisms and HCC in patients with hepatitis B virus (HBV)-related cirrhosis in the Chinese population.
|
27298104 |
2016 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our approach includes the study of the MBL2 gene genotype as well as ultra-deep sequencing of the HBV viruses obtained from the plasma of 50 treatment naïve patients with chronic HBV infection.
|
27824315 |
2016 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We studied allele and haplotype frequencies of -221C/G and codon 54G/A in MBL2 gene to reveal their relationship with the developing and progression of hepatitis B virus (HBV)-related liver diseases.
|
26857650 |
2016 |
Hepatitis B
|
0.100 |
Biomarker
|
disease |
BEFREE |
The innate immunity gene mannose-binding lectin2 (MBL2) has played an important role in hepatitis B virus (HBV) infection, and the relationship between MBL2 variants and hepatocellular carcinoma (HCC) risk has not yet been identified.
|
27557564 |
2016 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A meta-analysis was performed to examine the association between mbl2 polymorphisms and chronicity or progression of hepatitis B infection.
|
24116040 |
2013 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Tag single nucleotide polymorphisms (SNPs) were used to investigate the relationship between MBL2 gene polymorphisms and susceptibility to chronic hepatitis B virus (HBV) infection by comparing 996 chronic HBV infection cases to 301 acute infection controls.
|
23417614 |
2013 |
Hepatitis B
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our results provide preliminary evidence that inheritance of codon 52 genotypes and XY/O haplotype associated with low MBL level substantially determine the outcome of HBV infection in a sympatrically isolated South Indian population.
|
20193030 |
2010 |
Hepatitis B
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our findings may indicate that MBL has a protective role against HBV infection in the studied population.
|
20712490 |
2010 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
[Relationship between the gene mutations of mannose binding protein and the progression of hepatitis B infection].
|
18543229 |
2008 |
Hepatitis B
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mannose-binding lectin (MBL) is involved in host's response to several infections including hepatitis B but little is known about MBL and hepatitis C virus (HCV) infection.
|
18592362 |
2008 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
MBL gene polymorphism at codon 54 was not associated with the clearance of hepatitis B virus infection nor progression of disease in chronic hepatitis B virus infection.
|
15716605 |
2005 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Mannose binding lectin genotypes influence recovery from hepatitis B virus infection.
|
15994813 |
2005 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The roles of MBL and its gene (mbl2) polymorphisms, -221X/Y and codon 54A/B, in hepatitis B virus (HBV) infection were investigated in this study.
|
16231358 |
2005 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our results indicate that a mutation of the MBL gene might influence the clinical outcome of HBV infection in Vietnamese patients.
|
12517417 |
2003 |
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In white patients there is an association between codon 52 mutation of the MBL gene and persistent hepatitis B virus (HBV) infection.
|
11063157 |
2000 |