|
Pneumonia
|
0.100 |
Biomarker
|
disease |
BEFREE |
LT recipients of MBL-deficient livers had a higher risk of bacterial infection (incidence rate ratio [IRR] 1.48 [95% confidence interval 1.04-2.09], p = 0.028), pneumonia (IRR 2.4 [95% confidence interval 1.33-4.33], p = 0.013), and septic shock (IRR 5.62 [95% confidence interval 1.92-16.4], p = 0.002) compared with recipients of MBL-deficient livers.
|
28649744 |
2018 |
|
Pneumonia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Polymorphisms at genes coding for mannose binding lectin (MBL), MBL-associated serine protease 2, Fc-gamma receptors, and surfactant proteins A1, A2, and D were determined, and their potential association with pneumonia was analyzed.
|
25086072 |
2014 |
|
Pneumonia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Serum mannose-binding lectin (MBL) gene polymorphism and low MBL levels are associated with neonatal sepsis and pneumonia.
|
21681178 |
2012 |
|
Pneumonia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In patients with colorectal cancer (CRC), the MBL and MASP-2 serum levels are increased and high MASP-2 levels are associated with recurrence and poor survival, whereas low MBL levels predict post-operative pneumonia.
|
21198752 |
2011 |
|
Pneumonia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The available literature suggests that it may also be of benefit in MBL deficient patients with severe pneumonia.
|
20375630 |
2010 |
|
Pneumonia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Correlation of MBL and C-reactive protein levels in the acute phase of pneumonia also depended upon the MBL2 genotype.
|
19438602 |
2009 |
|
Pneumonia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The frequency of sufficient MBL genotypes was nonsignificantly higher in patients with pneumonia with Legionella sp and Mycoplasma pneumoniae.
|
18641104 |
2008 |
|
Pneumonia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No relationship was found between MBL genotype and the risk of nosocomial sepsis or pneumonia, even after correction for birth-weight, perhaps because of an insufficient correlation between genotype and the concentration of functional MBL.
|
18031556 |
2008 |
|
Pneumonia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Low MBL levels at birth are associated with an increased risk of early-onset sepsis, culture-proven sepsis and pneumonia during the first month of life.
|
17711490 |
2007 |
|
Pneumonia
|
0.100 |
Biomarker
|
disease |
BEFREE |
To define the contribution of polymorphisms in genes encoding tumor necrosis factor (TNF), mannose-binding lectin (MBL), and Fcgamma receptor IIa (FCGR2A) as well as clinical factors, to the development of pneumonia in patients with systemic lupus erythematosus (SLE).
|
17665457 |
2007 |
|
Pneumonia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
No correlation was observed between the levels of MBL and CRP in each phase, or with the pneumonia severity score.
|
16879241 |
2006 |
|
Pneumonia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We investigated the influence of MBL functional deficiency on the development of sepsis in 195 adult patients, 166 of whom had bloodstream infection and 35 had pneumonia.
|
17064281 |
2006 |
|
Pneumonia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We demonstrated that MBL protein could be directly measured in the BALF from the lungs of patients with pneumonia by means of enzyme-linked immunosorbent assay.
|
15249448 |
2004 |