MEF2D, myocyte enhancer factor 2D, 4209

N. diseases: 72; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 AlteredExpression disease BEFREE Myocyte enhancer factor 2D (MEF2D), an oncogene in liver cancer, has been shown to be aberrantly expressed in lung cancer. 29963192 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker disease BEFREE MEF2D might be a potential biomarker during chronic inflammation-lung cancer transition, predicting the risk of lung cancer among patients with chronic respiratory diseases. 28340574 2017
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 GeneticVariation disease BEFREE Further study revealed that miR-218, which was underexpressed in lung carcinoma, was predicted to bind the 3'-untranslated region (UTR) of MEF2D mRNA. miR-218 was shown to suppress the activity of luciferase with MEF2D 3'-UTR. 26409449 2016
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker disease BEFREE These results suggested that there is an autoregulatory circuit consisting of miR-1244 and MEF2D, which contributes to the progression of lung cancer. 26355845 2015