RAB8A, RAB8A, member RAS oncogene family, 4218

N. diseases: 69; N. variants: 3
Disease: Tumor necrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333516
Disease: Tumor necrosis
Tumor necrosis 		0.020 AlteredExpression phenotype BEFREE SK-MEL-2 cells transfected with sense VEGF (V+) expressed large amounts of mouse and human VEGF protein; V+ cells formed well-vascularized, rapidly growing tumors with minimal tumor necrosis. 9751633 1998
CUI: C0333516
Disease: Tumor necrosis
Tumor necrosis 		0.020 Biomarker phenotype BEFREE We measured the binding of 3H-labeled phorbol dibutyrate to membrane and cytosol fractions of TNF-treated SK-MEL-109 cells and found a transient redistribution of 3H-labeled phorbol dibutyrate binding from cytosol to membrane fractions in response to TNF. 2324095 1990