Disease: Stomach Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 AlteredExpression group BEFREE Patients with positive c-MET expression had significantly shorter PFS (11.5 vs. 17.6 months, P = 0.039) and OS (17.0 vs. 24.3 months, P = 0.043), and had gastric tumors with a larger MTV (70.8 ± 53.11 vs. 41.1 ± 52.32, P = 0.034) and TLG (428.39 ± 442.95 vs. 205.7 ± 354.40, P = 0.039), compared with those with negative c-MET expression. 31395059 2019
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 Biomarker group BEFREE MET status in synchronous liver metastasis (N = 36) was correlated with primary stomach tumors. 29790169 2018
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 AlteredExpression group BEFREE However, several factors can trigger such MET upregulation in a manner independent of HGF, suggesting that gastric tumors with MET overexpression are not necessarily MET driven. 26690587 2016
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 Biomarker group BEFREE Deregulated signaling via the MET receptor tyrosine kinase is abundant in gastric tumors, with up to 80% of cases displaying aberrant MET expression. 27185371 2016
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 AlteredExpression group BEFREE Finally, MET expression was evaluated by immunohistochemistry in a stomach tumor tissue microarray (TMA). 25874496 2015
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 Biomarker group BEFREE A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors. 21500189 2012
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 Biomarker group CTD_human Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification. 22729845 2012
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 Biomarker group CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947 2011
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 AlteredExpression group LHGDN Gastrin and c-met protein expression were significantly higher in gastric tumor tissue than in IM (P<0.0001). 14719064 2004
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 Biomarker group BEFREE The HGF-c-MET pathway plays a pivotal role in gastric tumor growth, invasion, metastasis and angiogenesis. 15026993 2004
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 GenomicAlterations group CGI