MGMT, O-6-methylguanine-DNA methyltransferase, 4255

N. diseases: 444; N. variants: 24
Disease: Atrial Premature Complexes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033036
Disease: Atrial Premature Complexes
Atrial Premature Complexes 		0.030 GeneticVariation disease BEFREE There was no relationship of hypermethylation of any gene, including MGMT, with G-to-A or C-to-T transitions in KRAS or P53, although APC hypermethylation was associated with P53 mutation (P < 0.0002). 18451217 2008
CUI: C0033036
Disease: Atrial Premature Complexes
Atrial Premature Complexes 		0.030 PosttranslationalModification disease BEFREE APC and MGMT promoter methylation data were consistent and reproducible throughout the dilutions and all three replicates in the methylated DNA dilution matrix and between two experiments in clinical samples. 19179456 2009
CUI: C0033036
Disease: Atrial Premature Complexes
Atrial Premature Complexes 		0.030 Biomarker disease BEFREE The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. 19309276 2009