Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022783
Disease: Vulvar Lichen Sclerosus
Vulvar Lichen Sclerosus
0.010 GeneticVariation disease BEFREE Conclusions are as follows: (i) the epigenetic inactivation of genes is a common event in vulvar SCC and is also present in adjacent lesions, implying a possible precursor role for these alterations; (ii) MGMT and RASSF2A hypermethylation are present exclusively in vulvar SCC and LS associated with SCC, and absent from isolated LS; and (iii) TSP-1 hypermethylation is a bad prognosis factor in vulvar SCC. 20734389 2011