MGMT, O-6-methylguanine-DNA methyltransferase, 4255

N. diseases: 444; N. variants: 24
Disease: Retinoblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		0.030 PosttranslationalModification disease BEFREE MGMT hypermethylation was present in 15% of the retinoblastoma samples, and the absence of MGMT hypermethylation was associated (P = .002) with retinoblastoma at advanced Reese-Ellsworth tumor stage. 15799820 2005
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		0.030 PosttranslationalModification disease BEFREE No methylation of MGMT promoter was detected in the two retinoblastoma cell lines (Y79, WERI-Rb1). 11980845 2002
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		0.030 PosttranslationalModification disease LHGDN No methylation of MGMT promoter was detected in the two retinoblastoma cell lines (Y79, WERI-Rb1). 11980845 2002
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		0.030 AlteredExpression disease BEFREE The exception was loss of RB mRNA, which may be associated with lack of MGMT mRNA. 1501894 1992