M5b Acute differentiated monocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The MLL/EB1 cells grew more slowly owing to increased apoptosis in vitro and induced acute monocytic leukemia with an incomplete penetrance and longer survival in vivo.
|
30974389 |
2019 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Generation of a MLL-AF9-specific stem cell model of acute monocytic leukemia.
|
27185517 |
2017 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Cooperation of MLL/AF10(OM-LZ) with PTPN11 activating mutation induced monocytic leukemia with a shorter latency in a mouse bone marrow transplantation model.
|
27859216 |
2017 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A bone marrow examination confirmed the diagnosis of acute monocytic leukemia with a t(11;19) MLL-ELL fusion transcript.
|
19405140 |
2009 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The occurrence of MLL gene rearrangement in acute megakaryoblastic leukemia (AML-M7, acute myeloid leukemia, French-American-British type M7) is very rare and limited to pediatric age: in particular, MLL-MLLT10 fusion, previously reported as characteristic of monocytic leukemia, has been reported in only one case of pediatric megakaryoblastic leukemia.
|
16111539 |
2005 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The MYO1F, unconventional myosin type 1F, gene is fused to MLL in infant acute monocytic leukemia with a complex translocation involving chromosomes 7, 11, 19 and 22.
|
15897884 |
2005 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Here, we report a second case--an infant acute monocytic leukemia (AML M5b)--with an MLL/GRAF fusion.
|
15382263 |
2004 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
MLL/SEPTIN6 chimeric transcript from inv ins(X;11)(q24;q23q13) in acute monocytic leukemia: report of a case and review of the literature.
|
12874781 |
2003 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Is t(10;11)(p11.2;q23) involving MLL and ABI-1 genes associated with congenital acute monocytic leukemia?
|
12547160 |
2002 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Fluorescence in situ hybridization (FISH) analysis in a case of infant acute monocytic leukemia M5 revealed a complex rearrangement between chromosomes 10 and 11, leading to the disruption of the MLL gene.
|
12127405 |
2002 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Analysis of MLL-derived transcripts in infant acute monocytic leukemia with a complex translocation (1;11;4)(q21;q23;p16).
|
10700861 |
2000 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Molecular analysis of the rearranged genome and chimeric mRNAs caused by the t(6;11)(q27;q23) chromosome translocation involving MLL in an infant acute monocytic leukemia.
|
10719372 |
2000 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with an MLL-AF9 translocation.
|
11066077 |
2000 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The mixed lineage leukemia (MLL) gene located at chromosome band 11q23 is frequently rearranged in patients with therapy-related acute monocytic leukemia who received topoisomerase II inhibitors.
|
10648423 |
2000 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Of 16 acute myeloid leukemia patients with trisomy 11 and rearrangement of MLL reported, our patient was the youngest in age and the only one with AMoL.
|
9209466 |
1997 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23).
|
9305600 |
1997 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rearrangements of the human trithorax gene (MLL, HRX, Htrx-1, All-1) were studied by Southern blotting in blast cells stored at presentation from 65 adults with de novo acute myelomonocytic (AML-M4) and acute monocytic leukemia (AML-M5).
|
7949133 |
1994 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A case of acute monocytic leukemia with t(11;17) involving a rearrangement of MLL-1 and a region proximal to the RARA gene.
|
8194047 |
1994 |
M5b Acute differentiated monocytic leukemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In the present study, we isolated chimeric cDNAs between the MLL and a gene designated MLLT3 at 9p22 from a cDNA library of an IMS-M1 cell line with a t(9;11)(p22;q23) translocation, a representative karyotypic abnormality seen in acute monocytic leukemia.
|
8414510 |
1993 |