MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005940
Disease: Bone Diseases
Bone Diseases
0.310 Biomarker group CTD_human Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. 17440987 2007
CUI: C0005940
Disease: Bone Diseases
Bone Diseases
0.310 Biomarker group BEFREE 3) A network of disorders and disease genes linked by known disorder-gene associations indicates that cardiovascular disease and bone disease are closely related, suggesting that a single drug such as bisphosphonate, acting on a single gene, MMP2, could have both bone and cardiovascular side effects different from the osteoclast inhibition that is characteristic of bisphosphonate. 19070762 2009