MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Disease: Ameloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002448
Disease: Ameloblastoma
Ameloblastoma 		0.040 AlteredExpression disease BEFREE Elevated hydrostatic pressure promotes ameloblastoma cell invasion through upregulation of MMP-2 and MMP-9 expression via Wnt/β-catenin signalling. 29964338 2018
CUI: C0002448
Disease: Ameloblastoma
Ameloblastoma 		0.040 Biomarker disease BEFREE This study was conducted to develop a new animal model of ameloblastoma and to address the role of tissue inhibitor of metalloproteinase-2 (TIMP-2) and matrix metalloproteinase-2 (MMP-2) in the growth and invasiveness of ameloblastomas. 19895658 2010
CUI: C0002448
Disease: Ameloblastoma
Ameloblastoma 		0.040 AlteredExpression disease BEFREE Of the MMP-2/TIMP-2/MMP-14 complex, a high expression of MMP-2, TIMP-2 and MMP-14 mRNA levels may contribute to the local invasive characteristics of ameloblastoma, whereas the local invasive capacity of ameloblastoma is more likely related to a high transcriptional levels of TIMP-2 and MMP-14. 19709349 2010
CUI: C0002448
Disease: Ameloblastoma
Ameloblastoma 		0.040 AlteredExpression disease BEFREE These results indicate that inhibition of MMP-2 activity suppresses the local invasiveness of ameloblastoma cells. 18588710 2008