MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 AlteredExpression disease BEFREE These results demonstrate that FBP may prevent bleomycin-induced PF development through reduced expression of collagen and other ECM components mediated by a reduced TIMP-1 and MMP2 expression. 31509566 2019
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 Biomarker disease BEFREE Relaxin attenuates silica-induced pulmonary fibrosis by regulating collagen type I and MMP-2. 23973652 2013
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 Biomarker disease CTD_human In this study, we examined the sequential expression of MMP-2, MMP-9 and TIMP-1 in a rat model of pulmonary fibrosis induced by PQ. 21468558 2011
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 AlteredExpression disease BEFREE These findings suggest that epimorphin contributes to repair of pulmonary fibrosis in nonspecific interstitial pneumonia, perhaps partly by inducing expression of matrix metalloproteinase 2, which is an important proteolytic factor in lung remodeling. 15651999 2005
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 AlteredExpression disease LHGDN These findings suggest that epimorphin contributes to repair of pulmonary fibrosis in nonspecific interstitial pneumonia, perhaps partly by inducing expression of matrix metalloproteinase 2, which is an important proteolytic factor in lung remodeling. 15651999 2005