|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.
|
31356534 |
2019 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We conducted a haplotype analysis to examine the role of common variation of MMP3 in myocardial infarction (MI) and a meta-analysis to combine available evidence on the association between the 5A/6A polymorphism (rs3025058) and coronary diseases.
|
19762026 |
2010 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to analyze the occurrence of the -1612 5A/6A, -376C/G, and Glu45Lys polymorphisms of MMP3 and the -1562C/T and R279Q polymorphisms of MMP9 and their relation to the risk of coronary heart disease (CHD; stenosis >/=50% of the diameter in at least one major coronary artery) in a Chinese Han population.
|
19438845 |
2009 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Combined impact of matrix metalloproteinase-3 and paraoxonase 1 55/192 gene variants on coronary artery disease in Turkish patients.
|
18830194 |
2008 |
|
Coronary heart disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Matrix metalloproteinase-3 and coronary remodelling: implications for unstable coronary disease.
|
17543900 |
2007 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to assess matrix metalloproteinase-3 (MMP3) gene variation in relation to the degree of coronary atherosclerosis and risk of myocardial infarction (MI) in patients with coronary artery disease.
|
12821236 |
2003 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We found no association between the 5A/6A polymorphism in the MMP-3 gene and risk of coronary heart disease.
|
14499230 |
2003 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The stromelysin-1 5A/6A promoter polymorphism is a disease marker for the extent of coronary heart disease.
|
12515907 |
2002 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Interaction between smoking and the stromelysin-1 (MMP3) gene 5A/6A promoter polymorphism and risk of coronary heart disease in healthy men.
|
12485468 |
2002 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The functional 5A/6A polymorphism of the stromelysin-1 promoter has been implicated as a potential genetic marker for the progression of angiographically determined atherosclerosis in patients with coronary artery disease.
|
11116068 |
2000 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The stromelysin-1 genotype was determined for 496 men with coronary artery disease and cholesterol levels between 4.0 and 8.0 mmol/L, participating in the Regression Growth Evaluation Statin Study (REGRESS) study, a clinical trial assessing the effect of the lipid-lowering drug pravastatin on the progression of atherosclerosis.
|
10190398 |
1999 |
|
Coronary heart disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study. Lopid Coronary Angiography Trial.
|
9699891 |
1998 |
|
Coronary heart disease
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Thus, the common 5A/6A polymorphism of the human stromelysin-1 promoter appears to play an important role in regulating stromelysin-1 gene expression and may be involved in the progression of coronary heart disease.
|
8662692 |
1996 |
|
Coronary heart disease
|
0.400 |
Biomarker
|
disease |
CTD_human |
|
|
|