MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Disease: Colonic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 Biomarker group RGD Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. 21268133 2011
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 ModifyingMutation group RGD Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis. 20428773 2010
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 AlteredExpression group LHGDN Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo. 17224907 2007
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 AlteredExpression group LHGDN Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells. 17186550 2007
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 Biomarker group LHGDN Effect of DPC4 gene on invasion and metastasis of colorectal carcinoma cells. 17151782 2006
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 AlteredExpression group BEFREE In contrast to the current paradigm, MMP-9 is expressed equally by cancer and stromal cells within human colon tumors. 16551873 2006
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.540 Biomarker group CTD_human Nobiletin, a citrus flavonoid, down-regulates matrix metalloproteinase-7 (matrilysin) expression in HT-29 human colorectal cancer cells. 15725655 2005