Progressive supranuclear palsy
|
0.420 |
GeneticVariation
|
disease |
BEFREE |
Meta-analysis revealed highly significant associations for PSP risk alleles of rs8070723 and rs1768208 with higher LRRC37A4 and MOBP brain levels, respectively.
|
27115769 |
2016 |
Progressive supranuclear palsy
|
0.420 |
GeneticVariation
|
disease |
BEFREE |
We identify new CBD susceptibility loci and show that CBD and PSP share a genetic risk factor other than MAPT at 3p22 MOBP (myelin-associated oligodendrocyte basic protein).
|
26077951 |
2015 |
Alcoholic Intoxication, Chronic
|
0.310 |
Biomarker
|
disease |
BEFREE |
Gene level disturbances in cellular and molecular networks impacted by alcohol and alcoholism pathology include transketolase (TKT), transferrin (TF), and myelin (e.g., MBP, MOBP, and MOG).
|
25655461 |
2015 |
Schizophrenia
|
0.310 |
AlteredExpression
|
disease |
BEFREE |
Correlation and factor analyses revealed that mRNA levels for genes that did exhibit differential expression in schizophrenia (MAG, CNP, SOX10, CLDN11, and PMP2), as opposed to those that did not (MOBP and MBP), loaded on separate factors.
|
16213148 |
2006 |
Refractory anemias
|
0.010 |
Biomarker
|
disease |
BEFREE |
MOBP RA+ patients had increased radial diffusivity in the superior corona radiata and midbrain, and reduced fractional anisotropy in the superior corona radiata as well as superior and inferior longitudinal fasciculi compared with noncarriers (p < 0.01).
|
24994843 |
2014 |
Rheumatoid Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
MOBP RA+ patients had increased radial diffusivity in the superior corona radiata and midbrain, and reduced fractional anisotropy in the superior corona radiata as well as superior and inferior longitudinal fasciculi compared with noncarriers (p < 0.01).
|
24994843 |
2014 |
Deuteranomaly
|
0.010 |
Biomarker
|
disease |
BEFREE |
We identify new CBD susceptibility loci and show that CBD and PSP share a genetic risk factor other than MAPT at 3p22 MOBP (myelin-associated oligodendrocyte basic protein).
|
26077951 |
2015 |
Behavioral variant of frontotemporal dementia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Eighty-one patients with sporadic bvFTD were genotyped for tauopathy-associated SNPs at rs8070723 (microtubule-associated protein tau [MAPT]) and rs1768208 (myelin-associated oligodendrocyte basic protein [MOBP]).
|
24994843 |
2014 |
Progressive supranuclear palsy
|
0.420 |
Biomarker
|
disease |
CTD_human |
We found significant previously unidentified signals (P < 5 × 10(-8)) associated with PSP risk at STX6, EIF2AK3 and MOBP.
|
21685912 |
2011 |
Amyotrophic Lateral Sclerosis
|
0.400 |
Biomarker
|
disease |
CTD_human |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
|
27455348 |
2016 |
Amyotrophic Lateral Sclerosis With Dementia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
|
27455348 |
2016 |
Amyotrophic Lateral Sclerosis, Guam Form
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
|
27455348 |
2016 |
Ophthalmoplegia, Progressive Supranuclear
|
0.300 |
Biomarker
|
disease |
CTD_human |
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
|
21685912 |
2011 |
Supranuclear Palsy, Progressive, 1
|
0.300 |
Biomarker
|
disease |
CTD_human |
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
|
21685912 |
2011 |
Progressive supranuclear palsy
|
0.420 |
GeneticVariation
|
disease |
GWASCAT |
We found significant previously unidentified signals (P < 5 × 10(-8)) associated with PSP risk at STX6, EIF2AK3 and MOBP.
|
21685912 |
2011 |
Progressive supranuclear palsy
|
0.420 |
GeneticVariation
|
disease |
GWASCAT |
Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases.
|
30089514 |
2018 |
Amyotrophic Lateral Sclerosis
|
0.400 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
|
27455348 |
2016 |
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
|
23535033 |
2014 |
Corticobasal degeneration
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
|
26077951 |
2015 |
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.
|
18839057 |
2008 |
AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder)
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.
|
28931804 |
2017 |
AMYOTROPHIC LATERAL SCLEROSIS 1
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.
|
28931804 |
2017 |
Amyotrophic Lateral Sclerosis, Sporadic
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.
|
28931804 |
2017 |
AMYOTROPHIC LATERAL SCLEROSIS 1, AUTOSOMAL RECESSIVE
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.
|
28931804 |
2017 |
Alcoholic Intoxication, Chronic
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Gene level disturbances in cellular and molecular networks impacted by alcohol and alcoholism pathology include transketolase (TKT), transferrin (TF), and myelin (e.g., MBP, MOBP, and MOG).
|
25655461 |
2015 |