Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002893
Disease: Refractory anemias
Refractory anemias
0.010 Biomarker disease BEFREE MOBP RA+ patients had increased radial diffusivity in the superior corona radiata and midbrain, and reduced fractional anisotropy in the superior corona radiata as well as superior and inferior longitudinal fasciculi compared with noncarriers (p < 0.01). 24994843 2014
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 Biomarker disease BEFREE MOBP RA+ patients had increased radial diffusivity in the superior corona radiata and midbrain, and reduced fractional anisotropy in the superior corona radiata as well as superior and inferior longitudinal fasciculi compared with noncarriers (p < 0.01). 24994843 2014
CUI: C4021107
Disease: Non-obstructive azoospermia
Non-obstructive azoospermia
0.100 GeneticVariation disease GWASDB A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia. 22197933 2011
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 AlteredExpression disease BEFREE Correlation and factor analyses revealed that mRNA levels for genes that did exhibit differential expression in schizophrenia (MAG, CNP, SOX10, CLDN11, and PMP2), as opposed to those that did not (MOBP and MBP), loaded on separate factors. 16213148 2006
AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder)
0.100 GeneticVariation disease GWASCAT Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. 28931804 2017
CUI: C1862939
Disease: AMYOTROPHIC LATERAL SCLEROSIS 1
AMYOTROPHIC LATERAL SCLEROSIS 1
0.100 GeneticVariation disease GWASCAT Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. 28931804 2017
Amyotrophic Lateral Sclerosis, Sporadic
0.100 GeneticVariation disease GWASCAT Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. 28931804 2017
AMYOTROPHIC LATERAL SCLEROSIS 1, AUTOSOMAL RECESSIVE
0.100 GeneticVariation disease GWASCAT Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. 28931804 2017
Behavioral variant of frontotemporal dementia
0.010 GeneticVariation disease BEFREE Eighty-one patients with sporadic bvFTD were genotyped for tauopathy-associated SNPs at rs8070723 (microtubule-associated protein tau [MAPT]) and rs1768208 (myelin-associated oligodendrocyte basic protein [MOBP]). 24994843 2014
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.310 Biomarker disease BEFREE Gene level disturbances in cellular and molecular networks impacted by alcohol and alcoholism pathology include transketolase (TKT), transferrin (TF), and myelin (e.g., MBP, MOBP, and MOG). 25655461 2015
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.310 Biomarker disease PSYGENET Gene level disturbances in cellular and molecular networks impacted by alcohol and alcoholism pathology include transketolase (TKT), transferrin (TF), and myelin (e.g., MBP, MOBP, and MOG). 25655461 2015
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
0.400 Biomarker disease CTD_human Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
0.400 GeneticVariation disease GWASCAT Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
Amyotrophic Lateral Sclerosis With Dementia
0.300 Biomarker disease CTD_human Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
Amyotrophic Lateral Sclerosis, Guam Form
0.300 Biomarker disease CTD_human Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
CUI: C0393570
Disease: Corticobasal degeneration
Corticobasal degeneration
0.100 GeneticVariation disease GWASCAT Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy. 26077951 2015
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.100 GeneticVariation disease GWASCAT Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. 23535033 2014
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.100 GeneticVariation disease GWASDB Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. 23535033 2014
Ophthalmoplegia, Progressive Supranuclear
0.300 Biomarker disease CTD_human Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. 21685912 2011
CUI: C4551863
Disease: Supranuclear Palsy, Progressive, 1
Supranuclear Palsy, Progressive, 1
0.300 Biomarker disease CTD_human Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. 21685912 2011
CUI: C0038868
Disease: Progressive supranuclear palsy
Progressive supranuclear palsy
0.420 GeneticVariation disease GWASCAT Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases. 30089514 2018
CUI: C0038868
Disease: Progressive supranuclear palsy
Progressive supranuclear palsy
0.420 GeneticVariation disease BEFREE Meta-analysis revealed highly significant associations for PSP risk alleles of rs8070723 and rs1768208 with higher LRRC37A4 and MOBP brain levels, respectively. 27115769 2016
Attention deficit hyperactivity disorder
0.100 GeneticVariation disease GWASDB Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. 18839057 2008
Attention deficit hyperactivity disorder
0.100 GeneticVariation disease GWASCAT Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. 18839057 2008
CUI: C0038868
Disease: Progressive supranuclear palsy
Progressive supranuclear palsy
0.420 Biomarker disease CTD_human We found significant previously unidentified signals (P < 5 × 10(-8)) associated with PSP risk at STX6, EIF2AK3 and MOBP. 21685912 2011