MPO, myeloperoxidase, 4353

N. diseases: 653; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.320 GeneticVariation disease BEFREE Previous findings on increased BC risk by packyears (p<0.001), coffee (p<0.001), cumulative AAs exposure (p = 0.041) and MnSOD (p = 0.009) and a decreased risk by MPO (p<0.008) were also confirmed by SEM analysis. 24722645 2014
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.320 Biomarker disease BEFREE These findings suggest that individual susceptibility of bladder cancer may be modulated by MPO and MnSOD polymorphisms, and that the combination of genetic factors involved in oxidative stress response with environmental carcinogens may play an important role in bladder carcinogenesis. 14729580 2004
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.320 Biomarker disease CTD_human Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk. 14729580 2004