MSX1, msh homeobox 1, 4487

N. diseases: 180; N. variants: 21
Disease: Tooth Agenesis, Familial ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 Biomarker disease BEFREE However, HYD-1 (Lys-Ile-Lys-Met-Val-Ile-Ser-Trp-Lys-Gly), an integrin antagonist, inhibited the KGF-enhanced epithelial adhesion and rete peg elongation. 28732179 2017
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 Biomarker disease GENOMICS_ENGLAND Mutations in the MSX1 gene in Turkish children with non-syndromic tooth agenesis and other dental anomalies. 25565750 2014
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 Biomarker disease BEFREE Genes affecting early tooth development (PAX9, MSX1, and AXIN2) are associated with familial tooth agenesis or oligodontia. 17552940 2007
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 GeneticVariation disease UNIPROT The role of MSX1 in human tooth agenesis. 12097313 2002
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 GeneticVariation disease UNIPROT We demonstrate that a mutation in the homeobox gene, MSX1, causes a common developmental anomaly, familial tooth agenesis. 8696335 1996
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 Biomarker disease GENOMICS_ENGLAND
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 Biomarker disease CTD_human
CUI: C3489529
Disease: Tooth Agenesis, Familial
Tooth Agenesis, Familial 		0.720 CausalMutation disease CLINVAR