|
Behavior Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Above all, our results revealed that deletion of homeoproteins Msx1 and Msx2 could lead to behavioral disorders and suggested that Msx1 and Msx2 played a crucial role in regulating the development and function of the neocortex.
|
31221479 |
2019 |
|
Patent ductus arteriosus
|
0.010 |
Biomarker
|
disease |
BEFREE |
The Nit-Occlud PDA (PFM Medical, Cologne, Germany), a nitinol coil patent ductus arteriosus (PDA) occluder, was approved by the Food and Drug Administration in 2013.
|
30511498 |
2019 |
|
Atrial Septal Defects
|
0.010 |
Biomarker
|
group |
BEFREE |
In this study, we used Msx2 conditional knockout (CKO) mice as a model and found that Msx2 deficiency in surface ectoderm induced ASD.
|
30683901 |
2019 |
|
Incontinence
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our findings suggest that visual BFB for training the PFM may be beneficial for women with or without incontinence.
|
31212987 |
2019 |
|
Periodontitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Experimental periodontitis was induced for 30 days in wild-type and Msx2 knock-in Swiss mice using Porphyromonas gingivalis infected ligatures.
|
31566253 |
2019 |
|
Abnormal behavior
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Above all, our results revealed that deletion of homeoproteins Msx1 and Msx2 could lead to behavioral disorders and suggested that Msx1 and Msx2 played a crucial role in regulating the development and function of the neocortex.
|
31221479 |
2019 |
|
Irido-corneal dysgenesis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Lens-specific conditional knockout of Msx2 in mice leads to ocular anterior segment dysgenesis via activation of a calcium signaling pathway.
|
30683901 |
2019 |
|
Resistant hypertensive disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Overall, we identified and replicated associations with RHTN in the MSX2, IFLTD1, and PTPRD regions, and combined these associations to create a genetic risk score.
|
30237584 |
2019 |
|
Pelvic Organ Prolapse
|
0.010 |
Biomarker
|
disease |
BEFREE |
The outcome measures were POP symptoms as measured by specific questions and Prolapse Quality of Life (P-QoL); POP severity as measured by POP-Q; and PFM function.
|
30311680 |
2019 |
|
Autism Spectrum Disorders
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this study, we used Msx2 conditional knockout (CKO) mice as a model and found that Msx2 deficiency in surface ectoderm induced ASD.
|
30683901 |
2019 |
|
ATRIAL SEPTAL DEFECT 1
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this study, we used Msx2 conditional knockout (CKO) mice as a model and found that Msx2 deficiency in surface ectoderm induced ASD.
|
30683901 |
2019 |
|
Malignant tumor of cervix
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Additionally, CC cell lines were transfected with small interfering RNAs (siRNAs) to downregulate the expression of HOX8 and assess cell proliferation using Cell Counting Kit-8.
|
29725445 |
2018 |
|
Foramen Ovale, Patent
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Between January 2012 and August 2016, 151 patients (mean age 41 ± 11 years) who had suffered from a cryptogenic thromboembolic event underwent transcatheter PFO closure with the PFM Nit-Occlud PFO device.
|
29068141 |
2018 |
|
Tongue Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
The present study also suggests that C-kit and Msx2 may be used as cell markers for postnatal tongue regeneration and self-repair, and may provide an approach for developing treatment methods for tongue diseases with a postnatal onset.
|
29375694 |
2018 |
|
Tuberculosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Mycothiol (MSH, AcCys-GlcN-Ins) is the main low-molecular weight (LMW) thiol of most Actinomycetes, including the human pathogen Mycobacterium tuberculosis that affects millions of people worldwide.
|
28372502 |
2018 |
|
B-Cell Lymphomas
|
0.010 |
Biomarker
|
group |
BEFREE |
This study aimed to determine Msh homeobox 2 (MSX2) and B cell lymphoma-2 (BCL2) expression patterns during anorectal development in anorectal malformations (ARM) and normal rat embryos, with the goals of determining the role of MSX2 and BCL2 in ARM pathogenesis.
|
30268882 |
2018 |
|
Orthostasis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
In the present sample, incontinent women have a greater anterior slope of the pelvis, and the greater the degree of anterior slope, the greater the electrical activity of the PFM, during rest, and in orthostasis.
|
30024050 |
2018 |
|
Tumor Progression
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
These novel observations suggested that overexpression of MSH factors affected the integrity of the DNA replication fork, causing genome instability phenotypes that could be important for promoting cancer progression.
|
29654124 |
2018 |
|
Cervix carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Additionally, CC cell lines were transfected with small interfering RNAs (siRNAs) to downregulate the expression of HOX8 and assess cell proliferation using Cell Counting Kit-8.
|
29725445 |
2018 |
|
Ostium secundum atrial septal defect
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Between January 2012 and August 2016, 151 patients (mean age 41 ± 11 years) who had suffered from a cryptogenic thromboembolic event underwent transcatheter PFO closure with the PFM Nit-Occlud PFO device.
|
29068141 |
2018 |
|
Teeth, Endodontically-Treated
|
0.010 |
Biomarker
|
disease |
BEFREE |
Most of crowns were PFM (63.8%) placed in molars (58.1%) and non endodontically treated teeth (65.4%).
|
29800638 |
2018 |
|
Anorectal Malformations
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Immunohistochemical staining of ARM embryos revealed that MSX2 was mainly expressed in the epithelium of the hindgut and urorectal septum (URS) on GD14.
|
30268882 |
2018 |
|
cervical cancer
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Additionally, CC cell lines were transfected with small interfering RNAs (siRNAs) to downregulate the expression of HOX8 and assess cell proliferation using Cell Counting Kit-8.
|
29725445 |
2018 |
|
Diabetic Nephropathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats.
|
29464183 |
2017 |
|
Congestive heart failure
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Development of CKD secondary to chronic heart failure (CHF), known as cardiorenal syndrome type 2 (CRS2), clinically associates with organ failure and reduced survival.
|
27297948 |
2017 |