Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Comprehensive analysis of Methylenetetrahydrofolate reductase C677T in younger acute lymphoblastic leukemia patients: A single-center experience.
|
30545275 |
2019 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association Between the 5,10-MTHFR 677C>T and RFC1 80G>A Polymorphisms and Acute Lymphoblastic Leukemia.
|
31499477 |
2019 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Use of MTHFR C677T polymorphism and plasma pharmacokinetics to predict methotrexate toxicity in patients with acute lymphoblastic leukemia.
|
29911750 |
2018 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association of methylenetetrahydrofolate reductase gene-gene interaction and haplotype with susceptibility to acute lymphoblastic leukemia in Chinese children.
|
27996344 |
2017 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between MTHFR microRNA binding site polymorphisms and methotrexate concentrations in Chinese pediatric patients with acute lymphoblastic leukemia.
|
28990296 |
2017 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The methylenetetrahydrofolate reductase 677T-1298C haplotype is a risk factor for acute lymphoblastic leukemia in children.
|
29390492 |
2017 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Methylenetetrahydrofolate reductase C677T and A1298C polymorphism and susceptibility to acute lymphoblastic leukemia in a cohort of Egyptian children.
|
25629981 |
2015 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Significance of 5,10-methylenetetrahydrofolate reductase gene variants in acute lymphoblastic leukemia in Indian population: an experimental, computational and meta-analysis.
|
25115513 |
2015 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Role of folate status and methylenetetrahydrofolate reductase genotype on the toxicity and outcome of induction chemotherapy in children with acute lymphoblastic leukemia.
|
25065700 |
2015 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
MTHFR gene polymorphism in acute lymphoblastic leukemia among North Indian children: a case-control study and meta-analysis updated from 2011.
|
24919644 |
2014 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Methylenetetrahydrofolate reductase polymorphisms and susceptibility to acute lymphoblastic leukemia in a Chinese population: a meta-analysis.
|
25342508 |
2014 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia.
|
24908438 |
2014 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We herein present results of analysis of common gene polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and glutathione S-transferase (GST) genes in a 10-year-old boy who developed very rare type of cancer, mixed phenotype acute leukemia, 6 years after treatment of acute lymphoblastic leukemia.
|
24276031 |
2014 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The effect of RFC G80A polymorphism in Cretan children with acute lymphoblastic leukemia and its interaction with MTHFR C677T and A1298C polymorphisms.
|
24237708 |
2014 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between methylenetetrahydrofolate reductase polymorphisms and the relapse of acute lymphoblastic leukemia: a meta-analysis.
|
24637499 |
2014 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The MTHFR C677T polymorphism and risk of acute lymphoblastic leukemia: an updated meta-analysis based on 37 case-control studies.
|
24377532 |
2013 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The influence of genetic RFC1, MS and MTHFR polymorphisms on the risk of acute lymphoblastic leukemia relapse in children and the adverse effects of methotrexate.
|
23986219 |
2013 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Methylenetetrahydrofolate reductase polymorphisms and risk of acute lymphoblastic leukemia-evidence from an updated meta-analysis including 35 studies.
|
22943282 |
2012 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Impact of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on methotrexate-induced toxicities in acute lymphoblastic leukemia: a meta-analysis.
|
22528943 |
2012 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children.
|
21495160 |
2012 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Variants of the MTHFR gene and susceptibility to acute lymphoblastic leukemia in children: a synthesis of genetic association studies.
|
22094326 |
2012 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The role of the methylenetetrahydrofolate reductase 677 and 1298 polymorphisms in Cretan children with acute lymphoblastic leukemia.
|
21117954 |
2011 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Methylenetetrahydrofolate reductase gene polymorphisms and acute lymphoblastic leukemia risk: a meta-analysis based on 28 case-control studies.
|
21702646 |
2011 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The authors describe the case of a 12-year-old male with acute lymphoblastic leukemia and a homozygous methylenetetrahydrofolate reductase C677T mutation, who developed subacute methotrexate-induced toxicity and cerebral venous thrombosis after receiving intrathecal methotrexate.
|
20121554 |
2010 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We investigated a possible association of MTHFR polymorphisms (677C>T and 1298A>C) and increased risk for acute lymphoblastic leukemia in 78 affected children.
|
20445408 |
2010 |