MUC7, mucin 7, secreted, 4589

N. diseases: 35; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.430 GeneticVariation disease BEFREE A logistic regression analysis showed that the MUC7*5-VNTR allele decreased the likelihood of a diagnosis of asthma (odds ratio, 0.173 [95% confidence interval, 0.041-0.737]; P < 0.018) and is not in a strong linkage disequilibrium with the rs9982010 (r = 0.03; odds ratio, 66; confidence interval, 5.913-736.72). 19820409 2009
CUI: C0004096
Disease: Asthma
Asthma
0.430 GeneticVariation disease BEFREE There was low haplotype diversity and strong association between each of the loci, and the MUC7*5 allele-carrying haplotype remained the one most strongly associated with asthma. 16759176 2006
CUI: C0004096
Disease: Asthma
Asthma
0.430 GeneticVariation disease BEFREE The MUC7*5 allele was rarer in the atopic asthmatics than in the atopic non-asthmatics (P = 0.014, OR for no asthma in atopic individuals 3.13, CI 1.01-6.10), and the difference in frequency between all asthmatics and all non-asthmatics was statistically significant (P = 0.009) while there was no difference between atopy and non-atopy (P = 0.199). 11378823 2001
CUI: C0004096
Disease: Asthma
Asthma
0.430 Biomarker disease HPO
CUI: C0004096
Disease: Asthma
Asthma
0.430 Biomarker disease CTD_human
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE Information is available on changes in the expression levels and distribution profiles of MUC1, MUC2, MUC3, MUC4, MUC5AC, MUC5B, MUC6 and MUC7 in tumors of the salivary glands; and of MUC1, MUC2 and MUC4 in HNSCC. 21723776 2011
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 AlteredExpression disease BEFREE The value of combined use of survivin, cytokeratin 20 and mucin 7 mRNA for bladder cancer detection in voided urine. 18026991 2008
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 AlteredExpression disease BEFREE The value of combined use of survivin, cytokeratin 20 and mucin 7 mRNA for bladder cancer detection in voided urine. 18026991 2008
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 GeneticVariation group BEFREE One gene is a tumour suppressor gene (HLF); two genes act as oncogenes (FGFR3 and LMO3); two genes are involved in matrix degradation (MMP12 and PTHLH); three genes are related to cell differentiation (SPRR1B, RTN1, and MUC7); and five genes have not been well characterized to date. 16915569 2006
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 Biomarker disease BEFREE These results suggest that MUC7 is a highly specific marker for bladder cancer and may be a useful method for the molecular staging and management of bladder cancer. 14678183 2004
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE These results suggest that MUC7 is a highly specific marker for bladder cancer and may be a useful method for the molecular staging and management of bladder cancer. 14678183 2004
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 Biomarker disease BEFREE Our results indicate that MUC7 is a potential marker for bladder cancer. 12837463 2003
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 Biomarker disease BEFREE The overall sensitivity of the MUC7 test for all bladder tumor cases was 66%. 12478110 2003
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 AlteredExpression group BEFREE Cells from the urine of 65 patients with bladder cancer, 15 patients with a negative bladder biopsy for bladder cancer, and 30 healthy volunteers were compared for the following parameters: tumor stage, grade, size, and number, urinary cytology, and expression of MUC7. 12837463 2003
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE Our results indicate that MUC7 is a potential marker for bladder cancer. 12837463 2003
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 AlteredExpression group BEFREE To provide information regarding the expression of these genes in squamous metaplasia and squamous cell carcinoma, we analyzed and compared the expression of MUC1-MUC7 genes by in situ hybridization in control respiratory mucosa and lesions associated with neoplasia (hyperplasia, metaplasia and dysplasia) and squamous cell carcinomas. 10738241 2000
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 AlteredExpression disease BEFREE Differential mucin MUC7 gene expression in invasive bladder carcinoma in contrast to uniform MUC1 and MUC2 gene expression in both normal urothelium and bladder carcinoma. 9865718 1998
Malignant neoplasm of urinary bladder
0.030 AlteredExpression disease BEFREE The value of combined use of survivin, cytokeratin 20 and mucin 7 mRNA for bladder cancer detection in voided urine. 18026991 2008
Malignant neoplasm of urinary bladder
0.030 Biomarker disease BEFREE These results suggest that MUC7 is a highly specific marker for bladder cancer and may be a useful method for the molecular staging and management of bladder cancer. 14678183 2004
Malignant neoplasm of urinary bladder
0.030 Biomarker disease BEFREE Our results indicate that MUC7 is a potential marker for bladder cancer. 12837463 2003
CUI: C0006430
Disease: Burning Mouth Syndrome
Burning Mouth Syndrome
0.020 Biomarker disease BEFREE MUC7 O-glycans and measured inflammatory biomarkers were found to be similar between BMS and controls. 31414088 2019
CUI: C0011334
Disease: Dental caries
Dental caries
0.020 AlteredExpression disease BEFREE Our study aimed to determine the relationship between dental caries in adults and levels of MUC5B and MUC7. 30745804 2019
CUI: C0333519
Disease: Caries (morphologic abnormality)
Caries (morphologic abnormality)
0.020 Biomarker disease BEFREE <b>Purpose</b>: Data currently available indicate the significance of salivary mucins MUC5B and MUC7 in the protection of teeth against caries. 30745804 2019
CUI: C0006430
Disease: Burning Mouth Syndrome
Burning Mouth Syndrome
0.020 GeneticVariation disease BEFREE The genotypic polymorphisms of IL-1β -511 and +3954, and of MUC7 VNTR, had no direct associations with the development of BMS. 27246755 2017
CUI: C0011334
Disease: Dental caries
Dental caries
0.020 GeneticVariation disease BEFREE This study does not show a correlation between the MUC7 genotypes and caries and oral hygiene of students. 22706105 2012