MUTYH, mutY DNA glycosylase, 4595

N. diseases: 156; N. variants: 174
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 GeneticVariation disease UNIPROT Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia coli Strain. 25820570 2015
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 AlteredExpression disease BEFREE These results suggested that MUTYH is a suppressor of mutations caused by 8OHG in gastric cells and that its reduced expression is associated with a poor prognosis in gastric cancer. 21826668 2011
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 GeneticVariation disease BEFREE The AluYb8MUTYH allele frequency can be associated with the early-onset breast and gastric cancer in the Chinese population. 22126480 2011
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 Biomarker disease BEFREE In summary, germline mutation at MSH2, MLH1, E-cadherin and MYH genes is a frequent event in the familial GC. 16929514 2006
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 PosttranslationalModification disease BEFREE Genetic alterations of the MYH gene in gastric cancer. 15273732 2004
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 GeneticVariation disease UNIPROT Genetic alterations of the MYH gene in gastric cancer. 15273732 2004
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.540 CausalMutation disease CGI