MX1, MX dynamin like GTPase 1, 4599

N. diseases: 71; N. variants: 7
Disease: Hepatitis B ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.060 GeneticVariation disease BEFREE Here, we show that for North African patients with chronic hepatitis, MX1 gene variation at position -123 may influence the outcome of HBV infection but not HCV infection.J. Med.Virol.89:647-652, 2017. 27458866 2017
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.060 GeneticVariation disease BEFREE This case-control study suggested that the haplotype GA in the MxA gene promoter region would increase the susceptibility to HBV infection in a Chinese population. 19744071 2009
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.060 Biomarker disease BEFREE GTPase activity is not essential for the interferon-inducible MxA protein to inhibit the replication of hepatitis B virus. 18668195 2008
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.060 GeneticVariation disease BEFREE Influences of MxA gene -88 G/T and IFN-gamma +874 A/T on the natural history of hepatitis B virus infection in an endemic area. 17845304 2007
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.060 AlteredExpression disease LHGDN Human MxA protein participates to the interferon-related inhibition of hepatitis B virus replication in female transgenic mice. 16168514 2005
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.060 AlteredExpression disease BEFREE We had previously shown that overexpression of the hepatitis B virus (HBV) capsid led to selective downregulation of MxA gene expression, suggesting a mechanism by which the virus escapes from the host defense system (O. Rosmorduc, H. Sirma, P. Soussan, E. Gordien, P. Lebon, M. Horisberger, C. Brechot and D. Kremsdorf, J. Gen. Virol.80:1253-1262, 1999). 11222692 2001