|
Malignant neoplasm of prostate
|
0.660 |
Biomarker
|
disease |
BEFREE |
The ability of AdMxi1 to suppress prostate tumor cell proliferation supports a role for Mxi1 loss in the pathogenesis of a subset of human prostate cancers.Prostate 47:194-204, 2001.
|
11351349 |
2001 |
|
Malignant neoplasm of prostate
|
0.660 |
GeneticVariation
|
disease |
BEFREE |
Commonly occurring loss and mutation of the MXI1 gene in prostate cancer.
|
9669667 |
1998 |
|
Malignant neoplasm of prostate
|
0.660 |
GeneticVariation
|
disease |
BEFREE |
Therefore, a substantial involvement of MXI1 gene alterations in the development of prostate cancer appears unlikely.
|
9458379 |
1998 |
|
Malignant neoplasm of prostate
|
0.660 |
Biomarker
|
disease |
BEFREE |
No mutations were found in these two important coding regions and we therefore conclude that MXI1 does not make a major contribution to prostate cancer susceptibility.
|
9376279 |
1997 |
|
Malignant neoplasm of prostate
|
0.660 |
Biomarker
|
disease |
BEFREE |
We detected a silent mutation in the HLH region, but no point mutations reflecting the functional change of Mxi1 were found in human prostate cancers.
|
8827088 |
1996 |
|
Malignant neoplasm of prostate
|
0.660 |
GeneticVariation
|
disease |
BEFREE |
MXI1 thus displays allelic loss and mutation in some cases of prostate cancer that may contribute to the pathogenesis or neoplastic evolution of this common malignancy.
|
7773287 |
1995 |
|
Malignant neoplasm of prostate
|
0.660 |
GeneticVariation
|
disease |
UNIPROT |
MXI1 thus displays allelic loss and mutation in some cases of prostate cancer that may contribute to the pathogenesis or neoplastic evolution of this common malignancy.
|
7773287 |
1995 |
|
Malignant neoplasm of prostate
|
0.660 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Malignant neoplasm of prostate
|
0.660 |
Biomarker
|
disease |
HPO |
|
|
|
|
Malignant neoplasm of prostate
|
0.660 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
Prostatic Neoplasms
|
0.360 |
Biomarker
|
group |
BEFREE |
The ability of AdMxi1 to suppress prostate tumor cell proliferation supports a role for Mxi1 loss in the pathogenesis of a subset of human prostate cancers.Prostate 47:194-204, 2001.
|
11351349 |
2001 |
|
Prostatic Neoplasms
|
0.360 |
Biomarker
|
group |
BEFREE |
We prospectively evaluated prostate tumors for loss of MXI1 by fluorescence in situ hybridization (FISH) and cytogenetic techniques.
|
9669667 |
1998 |
|
Prostatic Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
Sequence analysis revealed no somatic mutations in any of the six MXI1 coding exons, similar to findings in prostate tumors with MXI1 allelic loss.
|
9354456 |
1997 |
|
Prostatic Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
The oncogene MXI1 on chromosome band 10q24-25 is mutated in a proportion of prostate tumours and loss of heterozygosity occurs at this site, suggesting the location of a tumour suppressor in this region.
|
9376279 |
1997 |
|
Prostatic Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
A candidate tumor suppressor gene from this region, Mxi1 at 10q25, has recently been shown to be mutated in a small number of prostate tumors.
|
7585509 |
1995 |
|
Prostatic Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
We have detected mutations in the retained MXI1 alleles in four primary prostate tumours with 10q24-q25 deletions.
|
7773287 |
1995 |
|
Prostatic Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
|
|
|
|
Kidney Diseases
|
0.300 |
Biomarker
|
group |
CTD_human |
Inactivation of max-interacting protein 1 induces renal cilia disassembly through reduction in levels of intraflagellar transport 20 in polycystic kidney.
|
23316056 |
2013 |
|
Esophageal Neoplasms
|
0.220 |
Biomarker
|
group |
BEFREE |
Although mitotic checkpoint gene products (budding uninhibited by benzidazoles 1 homolog beta (BubR1) and mitotic arrest deficient-like 1 (Mad2)) have previously been reported to be involved in esophageal cancer, the association of NF-kappaB-activating kinase, caspase 10, and activator protein-1 with esophageal cancer has not been previously reported.
|
19558549 |
2009 |
|
Esophageal Neoplasms
|
0.220 |
Biomarker
|
group |
RGD |
Rat Mxi1 was isolated as a selective overexpressive message in rat esophageal cancer induced by N-nitrososarcosine ethyl ester using differential display and polymerase chain reaction cloning.
|
10849326 |
2000 |
|
Esophageal Neoplasms
|
0.220 |
Biomarker
|
group |
BEFREE |
Rat Mxi1 was isolated as a selective overexpressive message in rat esophageal cancer induced by N-nitrososarcosine ethyl ester using differential display and polymerase chain reaction cloning.
|
10849326 |
2000 |
|
Malignant neoplasm of upper third of esophagus
|
0.200 |
Biomarker
|
disease |
RGD |
Mxi1 is a potential cellular target of carcinogens and frequently mutated in experimental rat tumors and tumor cell lines.
|
10849326 |
2000 |
|
Malignant neoplasm of middle third of esophagus
|
0.200 |
Biomarker
|
disease |
RGD |
Mxi1 is a potential cellular target of carcinogens and frequently mutated in experimental rat tumors and tumor cell lines.
|
10849326 |
2000 |
|
Malignant neoplasm of lower third of esophagus
|
0.200 |
Biomarker
|
disease |
RGD |
Mxi1 is a potential cellular target of carcinogens and frequently mutated in experimental rat tumors and tumor cell lines.
|
10849326 |
2000 |
|
Malignant neoplasm of other specified part of esophagus
|
0.200 |
Biomarker
|
disease |
RGD |
Mxi1 is a potential cellular target of carcinogens and frequently mutated in experimental rat tumors and tumor cell lines.
|
10849326 |
2000 |