|
Thalassemia
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Our findings suggest that coinheritance of α-thalassemia or HBS1L-MYB locus variants may affect the clinical severity of Chinese <sup>G</sup>γ<sup>+</sup>(<sup>A</sup>γδβ)<sup>0</sup>-thalassemia.
|
31765637 |
2020 |
|
Bone Cysts, Aneurysmal
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
All components consistently showed diffuse p16, p63 and SOX2, variable cytokeratin (CK)7 and CK17 and rare Ber-EP4 and MYB expression; there was a substantially lower Ki67 index in pure ABCs and the ABC-like components.
|
31393622 |
2020 |
|
ovarian neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Expression of MYB was significantly correlated with good clinical outcome in OvCa and was negatively correlated with Slug expression in late-stage clinical specimens.
|
31570789 |
2020 |
|
Malignant neoplasm of ovary
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Expression of MYB was significantly correlated with good clinical outcome in OvCa and was negatively correlated with Slug expression in late-stage clinical specimens.
|
31570789 |
2020 |
|
Carcinoma, Ovarian Epithelial
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Expression of MYB was significantly correlated with good clinical outcome in OvCa and was negatively correlated with Slug expression in late-stage clinical specimens.
|
31570789 |
2020 |
|
Alopecia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of MYB in the skin induces alopecia and epidermal hyperplasia.
|
31758945 |
2019 |
|
Malignant neoplasm of stomach
|
0.010 |
Biomarker
|
disease |
BEFREE |
According to the overall survival analysis, three lncRNAs (AP002478.1, LINC00111, and LINC00313) and two mRNAs (MYB and COL1A1) functioned as prognostic biomarkers for patients with H. pylori (+) GC.
|
30370523 |
2019 |
|
Skin Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
MYB is a transcription factor expressed in hair follicle progenitor cells and found overexpressed in adnexal skin tumors.
|
31758945 |
2019 |
|
Epithelial hyperplasia of skin
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of MYB in the skin induces alopecia and epidermal hyperplasia.
|
31758945 |
2019 |
|
Adult Acute Basophilic Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The protein is frequently overexpressed in human leukemias, breast cancers, and other solid tumors suggesting that it is a bona fide oncogene. c-MYB is often overexpressed by translocation in human tumors with t(6;7)(q23;q34) resulting in c-MYB-TCRβ in T cell ALL, t(X;6)(p11;q23) with c-MYB-GATA1 in acute basophilic leukemia, and t(6;9)(q22-23;p23-24) with c-MYB-NF1B in adenoid cystic carcinoma.
|
30599775 |
2019 |
|
Childhood Acute Basophilic Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The protein is frequently overexpressed in human leukemias, breast cancers, and other solid tumors suggesting that it is a bona fide oncogene. c-MYB is often overexpressed by translocation in human tumors with t(6;7)(q23;q34) resulting in c-MYB-TCRβ in T cell ALL, t(X;6)(p11;q23) with c-MYB-GATA1 in acute basophilic leukemia, and t(6;9)(q22-23;p23-24) with c-MYB-NF1B in adenoid cystic carcinoma.
|
30599775 |
2019 |
|
Skin callus
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of <i>MdWRKY11</i> in apple callus could significantly promote anthocyanin accumulation, and the expression of some MYB transcription factors and structural genes increased significantly.
|
31310107 |
2019 |
|
Stomach Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
According to the overall survival analysis, three lncRNAs (AP002478.1, LINC00111, and LINC00313) and two mRNAs (MYB and COL1A1) functioned as prognostic biomarkers for patients with H. pylori (+) GC.
|
30370523 |
2019 |
|
Malignant neoplasm of kidney
|
0.010 |
Biomarker
|
disease |
BEFREE |
c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer.
|
31066170 |
2019 |
|
Water Stress
|
0.010 |
Biomarker
|
disease |
BEFREE |
A total of 211 transcription factors (TFs), including TF families involved in plant senescence, such as NAC, MYB, WRKY, and AP2/ERF members, as well as TFs related to water stress tolerance, were shown to be regulated during stem bending.
|
31331262 |
2019 |
|
Renal carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer.
|
31066170 |
2019 |
|
CHROMOSOME 8p11 MYELOPROLIFERATIVE SYNDROME
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
DNMT1 knockdown in stem cell leukemia/lymphoma (SCLL) cells increased miR-150-5p levels and reduced levels of the MYB proto-oncogene transcription factor, a key regulator of leukemogenesis.
|
31628193 |
2019 |
|
Anaplasia
|
0.010 |
Biomarker
|
disease |
BEFREE |
The MYB fusion was not detected in any of the classic EMCs (0/15) or in any of the EMCs with myoepithelial anaplasia (0/2) or high-grade transformation (0/1).
|
29135517 |
2018 |
|
Brain Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Transcription factor MYB is essential for the tumorigenesis of multiple cancers, especially leukemia, breast cancer, colon cancer, adenoid cystic carcinoma and brain cancer.
|
29675107 |
2018 |
|
Noninfiltrating Intraductal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Gene targets of these miRNAs, RhoA, PEG10 and MYB, were found to be more highly expressed in DCIS compared to IBC by qPCR and in MCF10A and MCF10DCIS.com cells compared to T47D cells by immunohistochemistry.
|
29214365 |
2018 |
|
Carcinoma, Papillary
|
0.010 |
Biomarker
|
disease |
BEFREE |
- To detect histologic and molecular differences separating NIFTP from follicular adenomas (FAs) and invasive carcinomas, particularly papillary carcinomas with extensive follicular growth (PTC-EFGs) and invasive encapsulated PTC-FV (IE-PTC-FV).
|
29582677 |
2018 |
|
Acute Promyelocytic Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Microarray data verify that the MYB expression was significantly higher in APL patient samples than in normal promyelocyte samples.
|
30335887 |
2018 |
|
Leukoencephalopathy, Progressive Multifocal
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We also find that PML/RARα increases the acetylation level of the promoter region of MYB.
|
30335887 |
2018 |
|
Lymphoma, Follicular
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
On the other hand, a germ-line MYB mutation was identified in a patient who developed myelodysplastic syndromes (MDS) after FL.
|
29666007 |
2018 |
|
Papilloma
|
0.010 |
Biomarker
|
disease |
BEFREE |
We also examined for the MYB-NFIB fusion by fluorescent in situ hybridization (ISH) and for human papilloma virus by ISH.
|
29533280 |
2018 |