MYOD1, myogenic differentiation 1, 4654

N. diseases: 106; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 GeneticVariation group BEFREE Rhabdomyosarcomas are malignancies associated with a rhabdomyoblastic phenotype which can be demonstrated morphologically or by immunohistochemistry for MYOD1 and myogenin. 31696361 2020
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 Biomarker group BEFREE Using four different groups of biopsies obtained from gastric body without history of H. pylori infection (Hp-), gastric body without cancer after H. pylori eradication (cancer-free body), gastric body with early gastric cancer diagnosed after H. pylori eradication (EGC body) and their paired samples from adjacent mucosa of cancer (EGC ADJ), methylation status of five candidate genes (MYOD1, SLC16A12, IGF2, RORA and PRDM5) was examined by the bisulfite pyrosequencing. 29978464 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 Biomarker group BEFREE Moreover, PUM target mRNAs impinge on human disease genes linked to cancer, neurological disorders and cardiovascular disease. 29165587 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 Biomarker group BEFREE Our findings suggest that acting, at least in part, through SPIN1 and SPIN3, PUM proteins contribute to a mechanism promoting normal human male germ cell apoptotic status and thus preventing cancer. 30197756 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 Biomarker group BEFREE As well as identifying genes showing aberrant DNA methylation in certain HN subtypes, we also detected six genes--DBC1, DIO3, FZD9, HS3ST2, MOS, and MYOD1--that were significantly hypermethylated in B-cell, T-cell, and myeloid malignancies. 19750229 2009
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 PosttranslationalModification group BEFREE MYOD1 promoter methylation occurs in various malignancies including colorectal cancer. 14767572 2004
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 PosttranslationalModification group BEFREE It is concluded that the detection of increased Myf-3 methylation is a sensitive and specific test of malignancy which may complement other molecular methods that are currently used for the assessment of clonality. 11368360 2001
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.370 CausalMutation group CGI