ATF3, activating transcription factor 3, 467

N. diseases: 228; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.310 Biomarker disease BEFREE The results indicated that multiple genes, including activating transcription factor 3 and WSC domain containing 2 and the phosphoinositide 3 kinase/protein kinase b signaling pathway and its downstream effectors may be common factors associated with depression, PTC and/or UF. 29805500 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.310 Biomarker disease PSYGENET In contrast, ATF3 or ATF4 overexpression in nucleus accumbens decreases emotional reactivity and increases depression-like behavior, consistent with the behavioral phenotype induced by CREB. 18305237 2008