NBN, nibrin, 4683

N. diseases: 291; N. variants: 194
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.620 GeneticVariation disease BEFREE In the single-locus analysis, two variants, the NBS1 rs1805794 (OR 1.42, 95% CI 1.15-1.76, P = 0.001), and RAD54L rs1048771 (OR 1.61, 95% CI 1.17-2.22, P = 0.002) were significantly associated with glioma risk. 26514363 2016
CUI: C0017638
Disease: Glioma
Glioma
0.620 CausalMutation disease CGI
CUI: C0017638
Disease: Glioma
Glioma
0.620 Biomarker disease HPO
CUI: C0017638
Disease: Glioma
Glioma
0.620 Biomarker disease GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
CUI: C0017638
Disease: Glioma
Glioma
0.620 Biomarker disease BEFREE SMAD3 silencing enhances DNA damage in radiation therapy by interacting with MRE11-RAD50-NBS1 complex in glioma. 30535026 2019