NBN, nibrin, 4683

N. diseases: 214; N. variants: 106
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease BEFREE In addition, our study provides suggestive evidence of an interaction between SNPs in MRE11A and NBS1 associated with NHL risk (OR = 0.51, 95% CI: 0.34-0.77, p = 0.0002). 25010664 2015
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease BEFREE Haplotypic variation in MRE11, RAD50 and NBS1 and risk of non-Hodgkin's lymphoma. 17169801 2007
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease LHGDN frequency of the mutation in the NBS1 carriers was indeed increased in patients with acute lymphoblastic leukemia and non-Hodgkin lymphoma 16152606 2006
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease BEFREE These findings imply that heterozygous NBS1 germline mutations may contribute significantly to the overall incidence of NHL, especially of the gastrointestinal tract, in Central Europe. 16998789 2006
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease LHGDN 6 additional carriers of the 657del5 mutation and 2 carriers of the pathogenic NBS1 R215W mutation were identified among 186 non-Hodgkin lymphoma patients from Central Poland. 16998789 2006
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease BEFREE The NBS1 mutation 657del5 on one allele was found in 3 of 270 patients with ALL and 2 of 212 children and adolescents with NHL; no carrier was found among 63 patients with Hodgkin lymphoma (HL). 16152606 2006
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 PosttranslationalModification disease BEFREE Mutations and molecular variants of the NBS1 gene in non-Hodgkin lymphoma. 12353271 2002
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 GeneticVariation disease BEFREE No evidence for a major role of heterozygous deletion 657del5 within the NBS1 gene in the pathogenesis of non-Hodgkin's lymphoma of childhood and adolescence. 10848790 2000
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.360 CausalMutation disease CGI