NBN, nibrin, 4683

N. diseases: 291; N. variants: 194
Disease: Prostate carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE NBN 657del5 founder mutation predisposes to breast and prostate cancer. 31410679 2019
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE The NBN 657del5 mutation predisposes to poor prognosis prostate cancer. 30590007 2019
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE The Nijmegen breakage syndrome (NBS1) gene was suggested as a prostate cancer susceptibility gene. 24510842 2014
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker disease BEFREE NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer. 25415046 2014
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE A mutation in NBS1 predisposes to aggressive prostate cancer. 23149842 2013
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE Germline mutations of BRCA2 and NBS1 genes cause inherited recessive chromosomal instability syndromes and predispose to prostate cancer of poor prognosis. 24096176 2013
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE The S706X mutation truncates the protein in a highly conserved region of NBN near the MRE11 binding site, thus suggesting a role for rare NBN mutations in prostate cancer susceptibility. 22864661 2012
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE DNA repair system and prostate cancer progression: the role of NBS1 polymorphism (rs1805794). 22413803 2012
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation disease BEFREE In this study, a number of analyses were done to determine whether mutations in NBS1 are associated with an increased risk for prostate cancer. 16702373 2006
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker disease BEFREE NBS1 is a prostate cancer susceptibility gene. 14973119 2004