NCAM1, neural cell adhesion molecule 1, 4684

N. diseases: 445; N. variants: 34
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET To explore the role of sequence variation affecting PSA-NCAM formation, we conducted a targeted re-sequencing study of a ∼ 100 kb region--including the entire ST8SIA2 gene and its region of interaction with NCAM1--in 48 Caucasian cases with bipolar disorder using the Roche 454 platform. 24651862 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 AlteredExpression disease BEFREE In addition, altered PSA-NCAM expression in brains of patients with schizophrenia or bipolar disorder indicates a functional dysregulation of glycosylation in mental illness. 24651862 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Alterations in NCAM expression or proteolytic cleavage have been linked to human neuropsychiatric disorders such as schizophrenia, bipolar disorder and Alzheimer's disease, and may contribute to cognitive dysfunction. 21515372 2011
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Both SNPs and splice variants in the NCAM1 gene were analysed in bipolar disorder and schizophrenia. 17413444 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease LHGDN Both SNPs and splice variants in the NCAM1 gene were analysed in bipolar disorder and schizophrenia. 17413444 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Several candidate genes for schizophrenia may also be associated with bipolar disorder: G72, DISC1, NRG1, RGS4, NCAM1, DAO, GRM3, GRM4, GRIN2B, MLC1, SYNGR1, and SLC12A6. 17239033 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE Single nucleotide polymorphisms (SNPs) in the NCAM1 gene were significantly associated with bipolar disorder in the Japanese population. 17413444 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE Our results suggest that genetic variations in NCAM1 or nearby genes could confer risks associated with bipolar affective disorder in Japanese individuals. 15050861 2004
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Our results suggest that genetic variations in NCAM1 or nearby genes could confer risks associated with bipolar affective disorder in Japanese individuals. 15050861 2004
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE CUX2, a potential regulator of NCAM expression: genomic characterization and analysis as a positional candidate susceptibility gene for bipolar disorder. 11353453 2001