|
Alzheimer disease, familial, type 3
|
0.010 |
Biomarker
|
disease |
BEFREE |
In addition, nucleolar chromatin regulatory proteins, nucleophosmin 1 (NPM1), upstream binding factor, and nucleolin accumulated in the ViPR body in late-stage Ad infection.
|
31365788 |
2020 |
|
Burkitt Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study aims to explore the effect of NCL on drug sensitivity and its potential mechanism in CA46 Burkitt's lymphoma (BL) cells.
|
31127617 |
2019 |
|
Coronary Arteriosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings provide translational relevance of the AMPK-NCL-miR-93/miR-484 axis in miRNA processing in EC health and coronary artery disease.
|
31182601 |
2019 |
|
Coronary heart disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings provide translational relevance of the AMPK-NCL-miR-93/miR-484 axis in miRNA processing in EC health and coronary artery disease.
|
31182601 |
2019 |
|
Yolk Sac Tumor
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Embryonal carcinomas and yolk sac tumors showed lower expression of NCL than seminomas indicated by H-score.
|
31513277 |
2019 |
|
Seminoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Embryonal carcinomas and yolk sac tumors showed lower expression of NCL than seminomas indicated by H-score.
|
31513277 |
2019 |
|
Testicular Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Nucleolin and nucleophosmin expression in seminomas and non-seminomatous testicular tumors.
|
31513277 |
2019 |
|
B-Cell Lymphomas
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Effect of nucleolin on adriamycin resistance via the regulation of B-cell lymphoma 2 expression in Burkitt's lymphoma cells.
|
31127617 |
2019 |
|
Embryonal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Embryonal carcinomas and yolk sac tumors showed lower expression of NCL than seminomas indicated by H-score.
|
31513277 |
2019 |
|
Adult Burkitt Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study aims to explore the effect of NCL on drug sensitivity and its potential mechanism in CA46 Burkitt's lymphoma (BL) cells.
|
31127617 |
2019 |
|
Childhood Burkitt Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study aims to explore the effect of NCL on drug sensitivity and its potential mechanism in CA46 Burkitt's lymphoma (BL) cells.
|
31127617 |
2019 |
|
Frontotemporal Lobar Degeneration
|
0.010 |
Biomarker
|
disease |
BEFREE |
Considering the growing evidence for altered autophagy in the pathogenesis of neurodegenerative disorders, our findings support a role of NCL genes in FTLD risk and suggest that MFSD8-associated lysosomal dysfunction may contribute to FTLD pathology.
|
30382371 |
2019 |
|
Coronary Artery Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings provide translational relevance of the AMPK-NCL-miR-93/miR-484 axis in miRNA processing in EC health and coronary artery disease.
|
31182601 |
2019 |
|
Parvovirus B19 (disease)
|
0.010 |
Biomarker
|
disease |
BEFREE |
Immunohistochemistry used monoclonal anti-CMV antibody (NCL-CMVpp65, Leica Biosystems, Wetzlar, Germany), anti-PVB19 antibody (NCL-PARVO, Leica Biosystems, Wetzlar, Germany), and anti-HSV1/HSV2 antibodies (NCL-HSV-1 and HSV2, Leica Biosystems, Wetzlar, Germany).
|
29113531 |
2019 |
|
Malignant tumor of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
Nucleolin facilitates nuclear retention of an ultraconserved region containing <i>TRA2β4</i> and accelerates colon cancer cell growth.
|
29928487 |
2018 |
|
Diabetes Mellitus
|
0.010 |
Biomarker
|
group |
BEFREE |
Conclusions- These results demonstrate novel mechanisms involving upregulation of long noncoding RNA Dnm3os, disruption of its interaction with nucleolin, and epigenetic modifications at target genes that promote macrophage inflammatory phenotype in diabetes mellitus.
|
29930005 |
2018 |
|
Diabetic Nephropathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our study provides evidence that CYP4B1-PS1-001 regulates the ubiquitination and degradation of NCL and thereby plays a critical role in the proliferation and fibrosis of MMCs, indicating that CYP4B1-PS1-001 and NCL may be promising prognostic biomarkers and molecular targets for the treatment of diabetic nephropathy.
|
30257240 |
2018 |
|
Hemorrhagic Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis.
|
30339712 |
2018 |
|
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein.
|
30464179 |
2018 |
|
Rett Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We confirmed by Western blot analysis that nucleolin protein levels are altered in RTT brain, but not in <i>Mecp2</i>-deficient mice.
|
30619462 |
2018 |
|
Diffuse Large B-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Moreover, combining nucleolin inhibitors: aptamer AS1411 or nucant N6L with doxorubicin reduced DLBCL cell survival.
|
28690315 |
2018 |
|
Secondary malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability.
|
29250796 |
2018 |
|
Cerebral atrophy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Computed tomography scanning and reconstruction verify that brain atrophy ovine CLN5 NCL originates in the occipital lobes with subsequent propagation throughout the whole cortex and these regional differences are reflected in the ICV loss.
|
30136763 |
2018 |
|
Adenocarcinoma of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fabrication of acetylated carboxymethylcellulose coated hollow mesoporous silica hybrid nanoparticles for nucleolin targeted delivery to colon adenocarcinoma.
|
30007600 |
2018 |
|
Breast adenocarcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
G4 aptamers designed against STAT3, nucleolin and SP1 inhibit STAT3 transcriptional activity in human breast adenocarcinoma MCF-7 cells, and all the studied aptamers inhibit TOP1-mediated relaxation of supercoiled plasmid DNA.
|
29208488 |
2018 |