|
Presenile dementia
|
0.030 |
Biomarker
|
disease |
BEFREE |
For people with dementia, it is essential to identify the right time to introduce ACP before NH admission.
|
28988561 |
2018 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
The difficulties in creating ACP rest in improving its delivery to the tumour site and it also must maintain a low toxicity profile.
|
30686254 |
2019 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
Even though ACP is a benign tumor, treatment is challenging because of the tumor's eloquent location.
|
28414888 |
2017 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.
|
28645939 |
2017 |
|
Obesity
|
0.030 |
Biomarker
|
disease |
BEFREE |
Specific disruption of the gene expressions of TNFα downstream signals TNFSF11A or NDUFAB1 in the MBH of diet-induced obese mice reverses mitochondrial elongation and reduces obesity.
|
28489068 |
2017 |
|
Obesity
|
0.030 |
Biomarker
|
disease |
BEFREE |
Our findings indicate that NDUFAB1 could be a novel mitochondrial target to prevent obesity and insulin resistance by enhancing mitochondrial metabolism.-Zhang, R., Hou, T., Cheng, H., Wang, X. NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism.
|
31530015 |
2019 |
|
Dementia
|
0.030 |
Biomarker
|
disease |
BEFREE |
For people with dementia, it is essential to identify the right time to introduce ACP before NH admission.
|
28988561 |
2018 |
|
Dementia
|
0.030 |
Biomarker
|
disease |
BEFREE |
We therefore aimed to further explore barriers and facilitators for ACP with community-dwelling people with dementia.
|
30115008 |
2018 |
|
Dementia
|
0.030 |
Biomarker
|
disease |
BEFREE |
Relative to white persons with dementia, African American persons with dementia were reported to have a lower preference for comfort care (81% vs. 58%) and lower rates of completion of legal ACP (89% vs. 73%).
|
31309906 |
2019 |
|
Cerebrovascular accident
|
0.020 |
Biomarker
|
group |
BEFREE |
Predictors of completing ADs included age (≥65 years; odds ratio, 4.8; 95% CI, 2.3-10.1), white race (odds ratio, 3.1; 95% CI , 1.2-7.8), milder poststroke disability (modified Rankin Scale score ≤1; odds ratio, 2.9; 95% CI , 1.3-6.4), having previously discussed ACP with a physician (odds ratio, 4.8; 95% CI , 2.0-11.7), and discussing risk of stroke recurrence (odds ratio, 2.2; 95% CI , 1.1-4.5).
|
30995885 |
2019 |
|
Cerebrovascular accident
|
0.020 |
Biomarker
|
group |
BEFREE |
In thoracic aortic surgery, postoperative incidence of stroke and mortality was similar between ACP and RCP, whereas a trend toward a reduction of TND incidence existed in ACP.
|
29625501 |
2019 |
|
Root Caries
|
0.020 |
Biomarker
|
disease |
BEFREE |
This study investigated the remineralization effect of experimental mint formulations containing bioactive agents (xylitol; green tea extract, GT; and amorphous calcium phosphate, ACP) in the progression of artificially induced root caries.
|
29414808 |
2018 |
|
Atherosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In conclusion, adults recommended initiation or intensification of antihypertensive medication by the ACC/AHA but not the ACP/AAFP guideline have high atherosclerotic cardiovascular disease risk that may be reduced through treatment initiation or intensification.
|
30595115 |
2019 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
There is a significant association between ACP(1) and cancer grade mainly due to ACP(1) genotypes carrying the *C allele that are much less represented in patients with low grade when compared with those with high grade.
|
22692348 |
2012 |
|
Dentin Sensitivity
|
0.010 |
Biomarker
|
disease |
BEFREE |
The application of CPP-ACP paste during at-home tooth bleaching with 20% CP was beneficial since its use reduced the TS and presented no deteriorating effect on the colour change.
|
30121734 |
2019 |
|
Heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
Together, our findings identify that NDUFAB1 is a crucial regulator of mitochondrial energy and ROS metabolism through coordinating the assembly of respiratory complexes and supercomplexes, and thus provide a potential therapeutic target for the prevention and treatment of heart failure.
|
31366990 |
2019 |
|
Congestive heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
Together, our findings identify that NDUFAB1 is a crucial regulator of mitochondrial energy and ROS metabolism through coordinating the assembly of respiratory complexes and supercomplexes, and thus provide a potential therapeutic target for the prevention and treatment of heart failure.
|
31366990 |
2019 |
|
Hepatolenticular Degeneration
|
0.010 |
Biomarker
|
disease |
BEFREE |
ACP Best Practice No 163. Wilson's disease: acute and presymptomatic laboratory diagnosis and monitoring.
|
11127261 |
2000 |
|
Chronic Lymphocytic Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
The combination reduced tumor proliferation, NF-κB signaling, and expression of BCL-xL and MCL-1 more potently than single-agent therapy.<b>Conclusions:</b> The combination of acalabrutinib and ACP-319 was superior to single-agent treatment in a murine CLL model, warranting further investigation of this combination in clinical studies.<i></i>.
|
28645939 |
2017 |
|
Hairy Cell Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Classically, AcPs have been divided into four types according to their sensitivity to tartrate and to their origin: erythrocytic, lysosomal, prostatic AcP, and an AcP enzyme that was first identified in hairy cell leukemia (HCL).
|
8127141 |
1994 |
|
Lymphoma
|
0.010 |
Biomarker
|
group |
BEFREE |
Here, we evaluated the activity of acalabrutinib (ACP-196) and ACP-319 (AMG-319), second generation inhibitors of Bruton tyrosine kinase (BTK) and PI3Kδ inhibitor, respectively, in lymphoma pre-clinical models.
|
31355927 |
2019 |
|
Osteoporosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The ACP recently issued guidelines for the treatment of low bone density or osteoporosis to prevent fractures.
|
29869039 |
2018 |
|
polyps
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Human herpesvirus 6 (HHV-6) was absent in control goup, and positive in ACP middle meatus on affected side was significantly higher than that in ACP polypous surface and ACP polyp group (P < 0.05).
|
31837561 |
2020 |
|
Dental White Spot
|
0.010 |
Biomarker
|
disease |
BEFREE |
The application of CPP-ACP and CPP-ACPF had a significant regenerative effect on the WSLs.
|
31116280 |
2019 |
|
Benign Neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Even though ACP is a benign tumor, treatment is challenging because of the tumor's eloquent location.
|
28414888 |
2017 |