Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.150 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.150 Biomarker disease BEFREE The tumor metastasis suppressor gene Drg-1 has been shown to suppress metastasis without affecting tumorigenicity in immunodeficient mouse models of prostate and colon cancer. 17178897 2006
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.150 Biomarker disease BEFREE On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models. 15184886 2004
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.150 AlteredExpression disease BEFREE The Drg-1 gene has been shown to suppress tumor metastasis in animal models of prostate and colon cancer, and the expression of this gene is significantly reduced with advancement of prostate and breast cancers in clinical setting. 15520163 2004
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.150 Biomarker disease BEFREE Inhibition of Drg1 may provide a new means to increase the sensitivity of colon cancer cells to CPT-11. 12124325 2002
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.150 Biomarker disease BEFREE We propose that Drg-1 suppresses colon cancer metastasis by inducing colon cancer cell differentiation and partially reversing the metastatic phenotype. 10676663 2000
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.100 GeneticVariation group GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
Malignant neoplasm of large intestine
0.100 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
CUI: C1319315
Disease: Adenocarcinoma of large intestine
Adenocarcinoma of large intestine
0.100 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
0.100 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
0.100 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
0.100 GeneticVariation phenotype GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
0.100 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
CUI: C0200633
Disease: Neutrophil count (procedure)
Neutrophil count (procedure)
0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
CUI: C0200641
Disease: Blood basophil count (lab test)
Blood basophil count (lab test)
0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.100 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.060 Biomarker disease BEFREE The tumor metastasis suppressor gene Drg-1 has been shown to suppress metastasis without affecting tumorigenicity in immunodeficient mouse models of prostate and colon cancer. 17178897 2006
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.060 AlteredExpression disease BEFREE The Drg-1 gene has been shown to suppress tumor metastasis in animal models of prostate and colon cancer, and the expression of this gene is significantly reduced with advancement of prostate and breast cancers in clinical setting. 15520163 2004
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.060 Biomarker disease BEFREE On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models. 15184886 2004
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.060 Biomarker disease BEFREE Inhibition of Drg1 may provide a new means to increase the sensitivity of colon cancer cells to CPT-11. 12124325 2002
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.060 Biomarker disease BEFREE We propose that Drg-1 suppresses colon cancer metastasis by inducing colon cancer cell differentiation and partially reversing the metastatic phenotype. 10676663 2000
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.060 AlteredExpression disease BEFREE Drg1 mRNA has a length of approximately 3 kb and is induced approximately 20-fold during in vitro differentiation of the colon carcinoma cell lines HT29-D4 and Caco-2. 9251681 1997