Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.150 GeneticVariation disease GWASCAT Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. 29228715 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.150 Biomarker disease BEFREE The tumor metastasis suppressor gene Drg-1 has been shown to suppress metastasis without affecting tumorigenicity in immunodeficient mouse models of prostate and colon cancer. 17178897 2006
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.150 Biomarker disease BEFREE On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models. 15184886 2004
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.150 AlteredExpression disease BEFREE The Drg-1 gene has been shown to suppress tumor metastasis in animal models of prostate and colon cancer, and the expression of this gene is significantly reduced with advancement of prostate and breast cancers in clinical setting. 15520163 2004
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.150 Biomarker disease BEFREE Inhibition of Drg1 may provide a new means to increase the sensitivity of colon cancer cells to CPT-11. 12124325 2002
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.150 Biomarker disease BEFREE We propose that Drg-1 suppresses colon cancer metastasis by inducing colon cancer cell differentiation and partially reversing the metastatic phenotype. 10676663 2000